Rapid and environmentally-friendly extraction of carotenoids from Blakeslea trispora

Wang, Hongbo; Zhang, Liwei; Luo, Jun; Yu, Liang

doi:10.1007/s10529-015-1920-3

Cited by 5 publications

(1 citation statement)

References 17 publications

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“…All experiments were performed in triplicate, and the averages of the GABA production were used as the responsive values. ANOVA evaluated the significant variation in GABA production in different culture media (Wang et al, 2015). A second-order polynomial regression model was calculated using BBD analysis.…”

Section: Determination Of the Concentrations Of Viable Cells Of B Subtilismentioning

confidence: 99%

An efficient process for co-production of γ-aminobutyric acid and probiotic Bacillus subtilis cells

Wang

Huang

Sun

et al. 2018

Food Sci Biotechnol

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This study was to establish an integrated process for the co-production of c-aminobutyric acid (GABA) and live probiotics. Six probiotic bacteria were screened and Bacillus subtilis ATCC 6051 showed the highest GABAproducing capacity. The optimal temperature and initial pH value for GABA production in B. subtilis were found to be 30°C and 8.0, respectively. A variety of carbon and nitrogen sources were tested, and potato starch and peptone were the preferred carbon and nitrogen sources for GABA production, respectively. The concentrations of carbon source, nitrogen source and substrate (sodium L-glutamate) were then optimized using the response surface methodology. The GABA titer and concentration of viable cells of B. subtilis reached 19.74 g/L and 6.0 9 10 8 cfu/mL at 120 h. The GABA titer represents the highest production of GABA in B. subtilis. This work thus demonstrates a highly efficient co-production process for GABA and probiotic B. subtilis cells.

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Section: Determination Of the Concentrations Of Viable Cells Of B Subtilismentioning

confidence: 99%