“…As of 2023, more than 160,000 human patients have been treated with the Tenex procedure, and fewer than 30 adverse events (mostly localized swelling) requiring medical attention were reported (Morrey B, personal communication, 2023; Tenex Health, Lake Forest, CA, File Data, 2023). The risk/benefit has been exceptional, with efficacy between 80% and 95% following a single procedure performed under local anesthesia ( Avella and Smith, 2012 ; Barnes, 2013 ; Koh et al , 2013 ; Nanos and Malanga, 2015 ; Patel, 2015 ; Morrey, 2017 , 2018 ; Freed et al , 2019 ; Walrod et al , 2020 ). PUD of tendinopathic tissue in human patients has demonstrated the advantage of excising nonstructural debris, thereby allowing regenerative cells to populate the newly cleared space ( Koh et al , 2013 ; Elattrache and Morrey, 2013 ; Barnes et al , 2015 ; Kamineni et al , 2015 ; Patel, 2015 ; Patel et al, 2015 ; Seng et al , 2016 ; Ostrom and Joseph, 2018 ; Freed et al , 2019 ).…”