Rapid and Sustained Resolution of Serous Retinal Detachment in Sturge-Weber Syndrome after Single Injection of Intravitreal Bevacizumab

Shoeibi, Nasser; Ahmadieh, Hamid; Abrishami, Mojtaba; Poorzand, Hoorak

doi:10.3109/09273948.2011.589022

Cited by 22 publications

(11 citation statements)

References 5 publications

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“…Intralesional Bevacizumab has been reported in the treatment of epistaxis in hereditary haemorrhagic telangiectasia (HHT) and intraorbital hemangiomas [38]. Intravenous Bevacizumab has been reported to be effective in the treatment of AVMs of patients with HHT, in radiation-induced cavernomas and in central nervous system hemangioblastomas [39][40][41][42].…”

Section: Vegf Pathway Inhibitors (Ie Bevacizumab)mentioning

confidence: 98%

Adjuvant role of anti-angiogenic drugs in the management of head and neck arteriovenous malformations

et al. 2015

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Section: Vegf Pathway Inhibitors (Ie Bevacizumab)mentioning

confidence: 98%

Adjuvant role of anti-angiogenic drugs in the management of head and neck arteriovenous malformations

et al. 2015

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“…[ 43 ] A single intravitreal bevacizumab injection has resulted in sustained resolution of exudative RD in Sturge-Weber syndrome over 20 months in a single case. [ 44 ]…”

Section: Diffuse Choroidal Hemangiomamentioning

confidence: 99%

Vascular tumors of the choroid and retina

Shanmugam

Ramanjulu

2015

Indian J Ophthalmol

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“…There is no definitive treatment regimen for exudative retinal detachment in patients with choroidal hemangiomas. Treatment options include radiotherapy [ 4 ], photodynamic therapy [ 5 ], oral propranolol [ 6 ], pegaptinib [ 7 ], and bevacizumab [ 8 ],[ 9 ].…”

Section: Introductionmentioning

confidence: 99%

Spontaneous exudative retinal detachment in a patient with sturge-weber syndrome after taking arginine, a supplement for erectile dysfunction

Bach

Gold²,

Villegas³

et al. 2014

Eye and Vis

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BackgroundPatients with Sturge-Weber syndrome can have ipsilateral diffuse or circumscribed choroidal hemangiomas. These hemangiomas have been seen to undergo spontaneous exudative or hemorrhagic retinal detachments. There is no definitive treatment for these types of retinal detachments, but radiotherapy, photodynamic therapy, oral propranolol, pegaptinib and bevacizumab have been used.Case presentationA 26-year-old male with Sturge-Weber Syndrome developed an exudative retinal detachment that occurred immediately after taking a supplement containing arginine. The patient was treated with intravitreal bevacizumab 1.25 mg in 0.05 ml solution. Resolution of the retinal detachment was seen after 4 treatments over a six-month period.ConclusionsArginine and other medications that cause a release of nitric oxide may lead to intravascular leakage and exudative retinal detachments in patients who have a choroidal hemangioma.Electronic supplementary materialThe online version of this article (doi:10.1186/s40662-014-0007-x) contains supplementary material, which is available to authorized users.

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Rapid and Sustained Resolution of Serous Retinal Detachment in Sturge-Weber Syndrome after Single Injection of Intravitreal Bevacizumab

Abstract: An early single dose of intravitreal bevacizumab is effective in the treatment of serous retinal detachment in SWS with good long-term results.

Cited by 22 publications

References 5 publications

Adjuvant role of anti-angiogenic drugs in the management of head and neck arteriovenous malformations

Adjuvant role of anti-angiogenic drugs in the management of head and neck arteriovenous malformations

Vascular tumors of the choroid and retina

Spontaneous exudative retinal detachment in a patient with sturge-weber syndrome after taking arginine, a supplement for erectile dysfunction

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