2024
DOI: 10.3390/molecules29081720
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Rapid Apta-Chromogenic Detection Method for Nitrofuran Metabolite Determination

Navarat Chaisri,
Chutikarn Jaengphop,
Ikuo Hirono
et al.

Abstract: Nitrofuran (NF) contamination in food products is a global problem resulting in the banned utilization and importation of nitrofuran contaminated products. A novel chromogenic detection method using a specific DNA aptamer with high affinity and specificity to nitrofurans was developed. Single-stranded DNA aptamers specific to nitrofuran metabolites, including 3-amino-2-oxazolidinone (AOZ), 3-amino-5-methylmorpholino-2-oxazolidinone (AMOZ), and 1-aminohydantoin (AHD), were isolated using magnetic bead-SELEX. Th… Show more

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