Rapid Atrial Fibrillation in the Emergency Department

Alsagaff, Mochamad Yusuf; Susilo, Hendri; Pramudia, Christian; Amadis, Muhammad Rafdi; Julario, Rerdin; Raharjo, Sunu Budhi; Dharmadjati, Budi Baktijasa; Lusida, Terrence Timothy Evan; Azmi, Yusuf; Doevendans, Pieter A.

doi:10.17925/hi.2022.16.1.12

Cited by 2 publications

(2 citation statements)

References 68 publications

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“…In this scenario, the ventricular rate of AF ranges between 60 and 100 beats per minute (bpm) and rarely causes hemodynamic instability. Thus, the treatment of AHF is more critical than the treatment of the arrhythmia and the emergency physician should seek for another precipitant, other than AF, for the worsening of HF [33].…”

Section: Af As An Innocent Bystander Of Ahfmentioning

confidence: 99%

The Optimal Management of Patients with Atrial Fibrillation and Acute Heart Failure in the Emergency Department

Velliou,

Sanidas,

Diakantonis

et al. 2023

Medicina

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Atrial fibrillation (AF) and acute heart failure (AHF) are two closely interrelated conditions that frequently coexist in a manifold manner, with AF serving either as the causative factor or as the consequence or even as an innocent bystander. The interplay between these two clinical conditions is complex, given that they share common pathophysiological pathways and they can reciprocally exacerbate each other, thus triggering a vicious cycle that worsens the prognosis and increases the thromboembolic risk. The optimal management of AF in the context of AHF in the emergency department remains a challenge depending on the time onset, as well as the nature and the severity of the associated symptoms. Acute rate control, along with early rhythm control, when indicated, and anticoagulation represent the main pillars of the therapeutic intervention. The purpose of this review is to elucidate the pathophysiological link between AF and AHF and accordingly present a stepwise algorithmic approach for the management of AF in AHF patients in the emergency setting.

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Section: Af As An Innocent Bystander Of Ahfmentioning

confidence: 99%

The Optimal Management of Patients with Atrial Fibrillation and Acute Heart Failure in the Emergency Department

Velliou,

Sanidas,

Diakantonis

et al. 2023

Medicina

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“…AF increases the risk of stroke by two to three times, and can also increase the risk of heart failure (Anter et al 2009, Kamel et al 2016, Alsagaff et al 2022. Identifying and screening for AF risk factors may help to prevent future disease and complications.…”

Section: Introductionmentioning

confidence: 99%

Five Single-Nucleotide Polymorphisms in the PITX2 Gene as Risk Factors for Atrial Fibrillation

Putra

Dharmadjati

Pikir

et al. 2023

FMI

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Highlights: A genetic variable has been identified as an atrial fibrillation risk factor Rs2200733 is a type of SNP that increases atrial fibrillation risk, whereas rs3853445, rs6838973, and rs17570669 have the reverse effect Abstract: Atrial fibrillation (AF) is a highly prevalent arrhythmia. The involvement of molecular mechanisms in increased AF risk remains uncertain. However, the paired-like homeodomain transcription factor 2 or pituitary homeobox 2 (PITX2) gene has been linked to AF development. A comprehensive search was carried out to identify all eligible case-control studies in order to assess the association between five single-nucleotide polymorphisms (SNPs) in the PITX2 gene and the risk of AF. This meta-analysis employed the Review Manager (RevMan) software version 5.3 (Cochrane). There were 13 clinical studies, with a total of 11,961 subjects, that met the inclusion criteria. These subjects consisted of 4,440 patients with AF and 7,521 controls. The meta-analysis of five SNP types in the PITX2 gene was done using crude odds ratios (ORs). This revealed that rs2200733 increased the risk of AF (OR=1.80; 95% CI=1.53-2.11; p=0.0005; I2=80%). On the other hand, the other three SNPs decreased the risk of AF, namely, rs385344 (OR=0.75; 95% CI=0.59-0.95; p=0.002; I2=85%), rs6838973 (OR=0.64; 95% CI=0.51-0.81; p=0.0001; I2=73%), and rs17570669 (OR=0.80; 95% CI=0.65-0.98; p=0.03; I2=70%). However, there was no significant association between rs10033464 and AF (OR=1.21; 95% CI=0.97-1.50; p=0.13; I2=83%). In conclusion, depending on the type, SNPs in the PITX2 gene correlate with AF risk factors, either by alleviating or reducing the risk.

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Rapid Atrial Fibrillation in the Emergency Department

Cited by 2 publications

References 68 publications

The Optimal Management of Patients with Atrial Fibrillation and Acute Heart Failure in the Emergency Department

The Optimal Management of Patients with Atrial Fibrillation and Acute Heart Failure in the Emergency Department

Five Single-Nucleotide Polymorphisms in the PITX2 Gene as Risk Factors for Atrial Fibrillation

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