<b><i>Introduction:</i></b> In learning to read, children learn to integrate orthographic, phonological, and semantic codes into highly specified and redundant lexical representations. The aim is to test a proposed model for the relationship between phonological awareness (PA) and rapid automatized naming (RAN) as mediated by word reading (WR) and spelling (SP) in children with developmental dyslexia (DD), attention deficit hyperactivity disorder (ADHD), and mild intellectual disability (ID). <b><i>Methods:</i></b> The relation between PA and RAN was found to be mediated by WR and SP in children with DD, ADHD, and mild ID. Three groups of children were included: DD children (<i>N</i> = 70), ADHD children (<i>N</i> = 68), and ID children (<i>N</i> = 69). This is a quantitative correlational, cross-sectional study investigating the strength and direction of relationships among proposed variables. <b><i>Results:</i></b> The relation between PA and RAN was found to be mediated by WR and SP. Based on their correlation analysis, the researcher concluded that there are significant correlations between PA, RAN, WR, and SP. PA correlates positively with RAN and SP. RAN correlates positively with WR and SP. <b><i>Conclusion:</i></b> The study extended our knowledge of the relationship between PA and RAN as mediated by WR and SP in children with DD, ADHD, and mild ID. In practice, this is conducive to promote the utilization of “PA” and “RAN” so as to improve the early literacy skills (WR and SP) among children with DD, ADHD, and mild ID.