Rapid chemical reduction synthesis of copper nanoclusters with blue fluorescence for highly sensitive detection of furazolidone

Abstract

Tannic acid (TA), as a stabilizing agent, was successfully utilized to establish blue‐emitting copper nanoclusters (TA‐Cu NCs) on the basis of a facile chemical reduction preparation method. Characterization results proved successful synthesis of TA‐Cu NCs with uniform size and excellent stability. TA‐Cu NCs exhibited a blue emission wavelength at 431 nm when excited at 364 nm. Interestingly, the as‐prepared TA‐Cu NCs were selectively quenched by furazolidone based on static quenching. In addition, this analysis platform for furazolidone detection had an excellent linear range from 0.5 to 120 μM with a detection limit of 0.074 μM (S/N = 3). Furthermore, the accuracy of this sensing method was successfully confirmed by detecting furazolidone in bovine serum samples, indicating that TA‐Cu NCs had bright application prospects.