Rapid containment of nosocomial transmission of a rare community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) clone, responsible for the Staphylococcal Scalded Skin Syndrome (SSSS)

Lamanna, Onofrio; Bongiorno, Dafne; Bertoncello, Lisa; Grandesso, Stefano; Mazzucato, Sandra; Pozzan, Giovanni Battista; Cutrone, Mario; Chirico, Michela; Baesso, Flavia; Brugnaro, Pierluigi; Cafiso, Viviana; Stefani, Stefania; Campanile, Floriana

doi:10.1186/s13052-016-0323-y

Cited by 17 publications

(9 citation statements)

References 27 publications

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“…With early diagnosis and management, mortality rate of SSSS is lower than 4% in children, and most skin lesions resolve by 2 weeks, as found in our patient. 1 , 3 – 6 …”

Section: Discussionmentioning

confidence: 99%

Staphylococcal scalded skin syndrome: A pediatric dermatology case report

Meshram

Kaur

Hura

2018

SAGE Open Medical Case Reports

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Staphylococcal scalded skin syndrome is a condition which predominantly affects children and causes a spectrum of skin lesions. We present a case of a 2-month-old infant with complaints of fever and fragile blisters over the body. The mucosal areas were spared. The diagnosis of staphylococcal scalded skin syndrome was reached on clinical grounds and culture report. The patient responded well to the treatment, which included an antibiotic (cloxacillin), an analgesic (paracetamol), and hydration with intravenous fluids. He was discharged after 8 days, with almost complete resolution of his skin lesions. Having a high clinical suspicion for staphylococcal scalded skin syndrome, early diagnosis/treatment, and following robust hygiene measures are imperative for the effective management of staphylococcal scalded skin syndrome. More efforts are needed to develop novel therapies for staphylococcal scalded skin syndrome.

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“…With early diagnosis and management, mortality rate of SSSS is lower than 4% in children, and most skin lesions resolve by 2 weeks, as found in our patient. 1 , 3 – 6 …”

Section: Discussionmentioning

confidence: 99%

Staphylococcal scalded skin syndrome: A pediatric dermatology case report

Meshram

Kaur

Hura

2018

SAGE Open Medical Case Reports

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“…Healthcare workers who are asymptomatic nasal carriers can sometimes be the source of MRSA outbreaks ( Wang et al, 2001 ; Vonberg et al, 2006 ; Haill et al, 2013 ; Lamanna et al, 2017 ). On the other hand, in nonoutbreak situations and in presence of control measures, healthcare workers are infrequently sources of transmission of S. aureus ( Price et al, 2017 ).…”

Section: Spread and Transmission Of S Aureusmentioning

confidence: 99%

Staphylococcus aureus Nasal Colonization: An Update on Mechanisms, Epidemiology, Risk Factors, and Subsequent Infections

et al. 2018

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Up to 30% of the human population are asymptomatically and permanently colonized with nasal Staphylococcus aureus. To successfully colonize human nares, S. aureus needs to establish solid interactions with human nasal epithelial cells and overcome host defense mechanisms. However, some factors like bacterial interactions in the human nose can influence S. aureus colonization and sometimes prevent colonization. On the other hand, certain host characteristics and environmental factors can predispose to colonization. Nasal colonization can cause opportunistic and sometimes life-threatening infections such as surgical site infections or other infections in non-surgical patients that increase morbidity, mortality as well as healthcare costs.

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“…Healthcare workers and hospital staffs can be asymptomatic nasal carriers for MRSA and their outbreaks. This hypothesis is supported by a double-blind randomized placebo-controlled trial in which mupirocin applied to decreased nose and hand carriage in healthcare workers [9,10].…”

Section: Introductionmentioning

confidence: 89%

Comparison of Incidence of Nasal Carriage of S Aureus in Children of Parents with Hospitals Employees and Other Jobs in Kindergartens in AJA University

Dormanesh¹

2018

PNBOA

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Background: Asymptomatic carriage of Staphylococcus aureus is common and one of the common sites (20-30%) is in the nose. On the other hand, it is a known cause for wide range of infectious disease. In current study, we evaluated the incidence of Staphylococcus aureus in the nostril of kids, in2 groups, first whose mothers were working in a hospital and second whose mothers were on other jobs in the kindergartens at the AJA University in 2018. Methods: In this cross-sectional study, all children aged 1-6 years were included. The demographic information was collected and Staphylococcus aureus was isolated and identified from nasal swabs via standard microbiologic methods. Result: In this study, 120 children were examined. The mean age of these children was 4.03 ± 1.04 years. Male: female ratio was 1.18:1. 76 (63 %) mothers were hospital's staffs and 55% had direct contact with the patients. Nasal cultures were positive for Staphylococcus aureus in 24 (20%) samples, of which 4 (3.3%) were MRSA. there was no relation between age and sex of kids and also their mother jobs with positive results. Conclusion: Staphylococcus aureus is still a common human pathogen with a considerable morbidity and mortality. Methicillin-resistant staphylococcus aureus (MRSA) may be seen in nasal carriers and it is important to consider hygiene and parents job when we have kids in a day care centre such as kindergartens.

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Rapid containment of nosocomial transmission of a rare community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) clone, responsible for the Staphylococcal Scalded Skin Syndrome (SSSS)

Cited by 17 publications

References 27 publications

Staphylococcal scalded skin syndrome: A pediatric dermatology case report

Staphylococcal scalded skin syndrome: A pediatric dermatology case report

Staphylococcus aureus Nasal Colonization: An Update on Mechanisms, Epidemiology, Risk Factors, and Subsequent Infections

Comparison of Incidence of Nasal Carriage of S Aureus in Children of Parents with Hospitals Employees and Other Jobs in Kindergartens in AJA University

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