2022
DOI: 10.21203/rs.3.rs-1879627/v1
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Rapid Detection of SARS-CoV-2 Variants by Molecular Clamping Technology Based RT-qPCR

Abstract: Given the challenges that fast-changing SARS-CoV-2 variants have caused in terms of rapid spread and reduced vaccine efficacy, a rapid and cost-effective assay that can detect new and emerging variants is greatly needed worldwide. We have successfully applied the xenonucleic acid-based molecular-clamping technology to develop a multiplex RT-qPCR assay for SARS-CoV-2 multivariant detection. The assay was tested on 649 nasopharyngeal swab samples that were collected from California and Ohio. The assay was able t… Show more

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