Rapid detection of β-conglutin with a novel lateral flow aptasensor assisted by immunomagnetic enrichment and enzyme signal amplification

Wu, Zhengzong; He, Deyun; Xu, Enbo; Jiao, Aiquan; Chughtai, Muhammad Farhan Jahangir; Jin, Zhengyu

doi:10.1016/j.foodchem.2018.07.011

Cited by 63 publications

(24 citation statements)

References 18 publications

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“…Apart from the popular optical and electrochemical sensors, other interesting options based on m-NPs have been applied for food analysis. The main interest of these alternative sensors lies in the use of a different transduction principles (i.e., quartz crystal microbalance (QCM) [80,81], magnetic relaxation switching (MRS) [82][83][84], photoelectrochemistry [85,86]) or/and their particular arrangement (i.e., portable and low-cost sensors based on screen-printed electrode (ScPE) [73,85,[87][88][89][90][91][92], lateral flow strip (LFS) [93][94][95][96], microfluidic platforms [86,[97][98][99], and smartphone analysis [95,100,101]). Some selected examples of these kinds of devices are included in Table 6 [80,81,85,86,94,95,98,100,101].…”

Section: Other Types Of Sensorsmentioning

confidence: 99%

“…This may be why not many LFS assays are commercially available. This kind of sensor has been employed together with m-NPs to analyse biogenic amines [93], oestrogenic compounds [94], globulin proteins [95] and botulinum neurotoxins [96] in beverages [93,96], milk [94,96], fish [94], meat [94] and legumes [95]. The main advantage of the introduction of m-NPs is the drastic increase in sensitivity and reduction of the LOD.…”

Section: Other Types Of Sensorsmentioning

confidence: 99%

“…The main advantage of the introduction of m-NPs is the drastic increase in sensitivity and reduction of the LOD. In this regard, Wu et al [95] applied three different LFS sensors (a conventional method, a sensitised system and a magnetically immobilised Apt (Figure 6)) for the detection of β-coglutin in lupine. In the classical version, the analyte was placed on the sample pad and flowed longitudinally by capillary action.…”

Section: Other Types Of Sensorsmentioning

confidence: 99%

“…Finally, regarding the use of sensors, their combination with smartphones should be highlighted [95,100,101]. That combination takes portability to another level involving a device that the vast majority of the population carries every day.…”

Section: Other Types Of Sensorsmentioning

confidence: 99%

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Recent Applications of Magnetic Nanoparticles in Food Analysis

et al. 2020

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Nanotechnology has become a topic of interest due to the outstanding advantages that the use of nanomaterials offers in many fields. Among them, magnetic nanoparticles (m-NPs) have been one of the most widely applied in recent years. In addition to the unique features of nanomaterials in general, which exclusively appear at nanoscale, these present magnetic or paramagnetic properties that result of great interest in many applications. In particular, in the area of food analysis the use of these nanomaterials has undergone a considerable increase since they can be easily separated from the matrix in sorbent-based extractions, providing a considerable simplification of the procedures. This allows reducing cost and giving fast responses, which is essential in the food trade to guarantee consumer safety. These materials can also be easily tunable, providing higher selectivity. Moreover, their particular electrical, thermal and optical characteristics allow enhancing sensor signals, increasing the sensitivity of the approaches based on this type of device. The aim of this review article is to summarise the most remarkable applications of m-NPs in food analysis in the last five years (2016–2020) showing a general view of the use of such materials in the field.

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Section: Other Types Of Sensorsmentioning

confidence: 99%

Section: Other Types Of Sensorsmentioning

confidence: 99%

Section: Other Types Of Sensorsmentioning

confidence: 99%

Section: Other Types Of Sensorsmentioning

confidence: 99%

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Recent Applications of Magnetic Nanoparticles in Food Analysis

et al. 2020

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“…Pin connections have been widely applied in many engineering fields [ 1 , 2 ]. Compared with other types of connection forms, pin connections have the advantages of low cost, simplicity, and facilitation of disassembly for repair [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Wear Degree Quantification of Pin Connections Using Parameter-Based Analyses of Acoustic Emissions

Wang

Huo

Song

2018

Sensors

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Pin connections are commonly used in many engineering fields, and continuous operation may cause severe wear on the pins and may lead to their eventual fracture, if undetected. However, a reliable nonintrusive real-time method to monitor the wear of pin connections is yet to be developed. In this paper, acoustic emission (AE)-based parametric analysis methods, including the logarithm of the cumulative energy (LAE), the logarithm of the slope of cumulative energy (LSCE), the b-value method, the Ib-value method, and the fast Fourier transformation (FFT), were developed to quantify the wear degree of pin connections. The b-value method offers a criterion to quickly judge whether severe wear occurs on a pin connection. To assist the research, an experimental apparatus to accelerate wear test of pin connections was designed and fabricated. The AE sensor, mounted on the test apparatus in a nondestructive manner, is capable of real-time monitoring. The micrographs of the wear of pins, and the surface roughness of pins, verified that the values of the max LAE and the max LSCE became larger as the wear degree of pin connections increased, which means different values of the max LAE and the max LSCE can reflect different wear degree of pin connections. Meanwhile, the results of the micrographs and surface roughness confirmed that the b-value is an effective method to identify severe wear, and the value “1” can be used as a criterion to detect severe damage in different structures. Furthermore, the results of spectrum analysis in the low frequency range showed that the wear frequency was concentrated in the range of 0.01 to 0.02 MHz for the pin connection. This study demonstrated that these methods, developed based on acoustic emission technique, can be utilized in quantifying the wear degree of pin connections in a nondestructive way.

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Advances in nanoparticle‐based lateral flow immunoassay for point‐of‐care testing

Lou

Fan

Jiang

et al. 2022

VIEW

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As a representative technology for point‐of‐care testing (POCT), lateral flow immunoassay (LFIA) has been broadly used to detect analytes in many fields. However, its clinical application is severely limited by the unsatisfactory sensitivity, which makes it difficult to obtain accurate results when detecting biomarkers of trace levels, especially in complex matrices. Nanoparticles have been introduced into LFIA for years and become an indispensable part, acting not only as carriers that load and enrich biomolecules, such as antibodies and dyes, but also a miniature platform applied for creative design and construction of nanoprobes. Due to the unique properties at the nanoscale, including the mimetic enzyme activity, the characteristic plasma resonance spectrum and so on, nanomaterials exhibit great potential in the development of novel LFIA and high‐sensitivity detection.

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Rapid detection of β-conglutin with a novel lateral flow aptasensor assisted by immunomagnetic enrichment and enzyme signal amplification

Cited by 63 publications

References 18 publications

Recent Applications of Magnetic Nanoparticles in Food Analysis

Recent Applications of Magnetic Nanoparticles in Food Analysis

Wear Degree Quantification of Pin Connections Using Parameter-Based Analyses of Acoustic Emissions

Advances in nanoparticle‐based lateral flow immunoassay for point‐of‐care testing

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