Rapid Diagnosis of Bacteremic Pneumococcal Infections in Adults by Using the Binax NOW
            <i>Streptococcus pneumoniae</i>
            Urinary Antigen Test: a Prospective, Controlled Clinical Evaluation

Smith, Michael D.; Derrington, Petra; Evans, Rachel; Creek, M.; Morris, Rhonwen; Dance, David A. B.; Cartwright, Keith

doi:10.1128/jcm.41.7.2810-2813.2003

Cited by 200 publications

(130 citation statements)

References 14 publications

(14 reference statements)

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“…Moreover, diagnoses of pneumococcal infections using pneumococcal urinary antigen test with specimens other than urine such as middle ear fluids, nasopharyngeal secretions, pleural fluids, pericardial fluid, and blood cultures have been reported (4-6, 13). Although pneumococcal urinary antigen tests are significantly greater in patients with pneumonia (87%) than in patients with other pneumococcal infections (70%) (14), positivity of pneumococcal urinary antigen test can indicate pneumococcal infections other than pneumonia. Reported sensitivity for pneumococcal bacteremia was high at 82% (14).…”

Section: Discussionmentioning

confidence: 99%

“…Although pneumococcal urinary antigen tests are significantly greater in patients with pneumonia (87%) than in patients with other pneumococcal infections (70%) (14), positivity of pneumococcal urinary antigen test can indicate pneumococcal infections other than pneumonia. Reported sensitivity for pneumococcal bacteremia was high at 82% (14). Moreover, we should clarify the past history of pneumococcal pneumonia when pneumococcal urinary antigen test is positive.…”

Section: Discussionmentioning

confidence: 99%

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Pneumococcal Vertebral Osteomyelitis and Psoas Abscess in a Patient with Systemic Lupus Erythematosus Disclosing Positivity of Pneumococcal Urinary Antigen Assay

et al. 2011

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A 53-year-old woman with systemic lupus erythematosus presented with a 3-day history of fever and coughing. Diagnosis of pneumococcal bronchitis was made based on symptoms and positivity of pneumococcal urinary antigen test. On day 3, severe low back pain acutely occurred. Pneumococcal vertebral osteomyelitis and psoas abscess was diagnosed 17 days later by yield of penicillin-susceptible S. pneumoniae strain in blood cultures and drainage fluid. Although pneumococcal urinary antigen test is a useful tool for the diagnosis of pneumococcal pneumonia, we should consider the possibility of pneumococcal infections other than pneumonia or overwhelming bacteremia in immunosuppressive patients when urinary antigen test is positive.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Pneumococcal Vertebral Osteomyelitis and Psoas Abscess in a Patient with Systemic Lupus Erythematosus Disclosing Positivity of Pneumococcal Urinary Antigen Assay

et al. 2011

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“…Improved laboratory diagnostic methods like antigen assays, rapid diagnostic kits and noninvasive procedures like urinary antigen detection test have demonstrated successful identification of respiratory pathogens and hence must be inducted in the clinical practice. [36][37][38] Incidence of ARI and malnutrition can be reduced with necessary and timely interventions. We need to teach proper hand-washing techniques to the concerned caretakers of the children as data suggests a strong relation between hand-washing and respiratory infections.…”

Section: Recommendationsmentioning

confidence: 99%

Clinico-epidemiological profile of acute respiratory infections and malnutrition in urban and rural population of central India

Jawade

Sukhsohale

Jawade

et al. 2016

Int J Contemp Pediatr

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Background: Acute respiratory infections (ARI) and Malnutrition in children have tremendous burden on the health care sector of developing nations including India. The intensity with which these conditions are holding grip in the community is indeed a matter of concern and hence developing nations should develop an insight to assess the severity of it has become a necessity.Methods: A hospital based cross sectional study was carried out in children aged 0-14 years. Children were clinically assessed and diagnosis was made as URTI or LRTI Also anthropometry was performed and accordingly children were divided into categories of no malnutrition (NM), severe acute malnutrition (SAM) and moderate acute malnutrition (MAM) in ‘under 5’ years age children according to WHO guidelines, whereas children aged ‘above 5’ years were categorized as per the IAP guidelines.Results: It was observed that most of the mothers of children were illiterate with inadequate or absent ventilation and use of biomass fuels (chulha) for cooking purpose in households of rural children. The proportion of malnutrition was found to be equal in Under 5 children. In ‘above 5 years’ age study subjects, 52.4% of urban study subjects were normal as compared to 16.7% of rural study subjects.Conclusions: Our study implies that ARI and Malnutrition definitely is more prevalent in the pediatric population. Prevalence of URTI was found to be on a higher side in the rural population and LRTI prevalence was found to be higher in the urban population. Similarly, the prevalence of malnutrition was almost similar in ‘Under 5’ aged children, whereas the prevalence of malnutrition in ‘Above 5’ aged children was higher in the rural population than urban population.

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“…It has sensitivity of 80% or more in adults and children when positive blood cultures are used as reference standard. [50][51][52][53][54] Rationale for the study…”

Section: Diagnostic Tests For Streptococcus Pneumoniaementioning

confidence: 99%

Randomised controlled trial and health economic evaluation of the impact of diagnostic testing for influenza, respiratory syncytial virus and Streptococcus pneumoniae infection on the management of acute admissions in the elderly and high-risk 18- to 64-year-olds

Nicholson

Abrams

Batham

et al. 2014

Health Technology Assessment

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Rapid Diagnosis of Bacteremic Pneumococcal Infections in Adults by Using the Binax NOW Streptococcus pneumoniae Urinary Antigen Test: a Prospective, Controlled Clinical Evaluation

Cited by 200 publications

References 14 publications

Pneumococcal Vertebral Osteomyelitis and Psoas Abscess in a Patient with Systemic Lupus Erythematosus Disclosing Positivity of Pneumococcal Urinary Antigen Assay

Pneumococcal Vertebral Osteomyelitis and Psoas Abscess in a Patient with Systemic Lupus Erythematosus Disclosing Positivity of Pneumococcal Urinary Antigen Assay

Clinico-epidemiological profile of acute respiratory infections and malnutrition in urban and rural population of central India

Randomised controlled trial and health economic evaluation of the impact of diagnostic testing for influenza, respiratory syncytial virus and Streptococcus pneumoniae infection on the management of acute admissions in the elderly and high-risk 18- to 64-year-olds

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