Rapid Diagnosis of Intravascular Catheter-Related Sepsis

Collignon, Peter; Chan, Rachael; Munro, Rosemary

doi:10.1001/archinte.1987.00370090085015

Cited by 43 publications

(7 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The two procedures that have been more extensively evaluated are the Gram and the acridine fluorescent stains. Although some authors have found a good correlation between these techniques and the culture of the tip, with sensitivity, specificity and negative predictive value over 85% [32–34], others have not corroborated these results, obtaining low sensitivity rates, and questioning these methods arguing that they are time consuming, require catheter withdrawal, and are not applicable to all types of catheters (in 10% of catheters these methods cannot be applied due to technical problems) [35,36].…”

Section: Definitions and Diagnosis Of Catheter‐related Infectionsmentioning

confidence: 99%

See 1 more Smart Citation

A critical approach to the pathogenesis, diagnosis, treatment and prevention of catheter-related bloodstream infections and nosocomial endocarditis

Fortün

Navas

1999

Clinical Microbiology and Infection

View full text Add to dashboard Cite

Section: Definitions and Diagnosis Of Catheter‐related Infectionsmentioning

confidence: 99%

“…Their explanation for this finding is that the superficial colonization may be a dynamic process [30]. On the other hand, some authors have confirmed by means of molecular diagnostic techniques the role of the superficial cultures in the pathogenesis of catheterrelated infections [33].…”

Section: Skin and Hub Culturesmentioning

confidence: 99%

A critical approach to the pathogenesis, diagnosis, treatment and prevention of catheter-related bloodstream infections and nosocomial endocarditis

Fortün

Navas

1999

Clinical Microbiology and Infection

View full text Add to dashboard Cite

“…Line tips can also be stained directly with Gram's stain 44 or acridine orange stain. 45 These techniques give quick results, and permit a view of the internal and external surface of the catheter.…”

Section: Culture Of Cathetersmentioning

confidence: 99%

Diagnosis and management of catheter‐related bloodstream infections due to Staphylococcus aureus

Gosbell¹

2005

Internal Medicine Journal

View full text Add to dashboard Cite

Intravenous catheters are essential to modern medical care but frequently cause complications, the most important of which is infection, commonly due to Staphylococcus aureus. It is estimated at least 3000 episodes of catheter-related bloodstream infection occur annually in Australia, and 9% to 25% of patients with such infections die. Infection rates vary depending on the type of device, with the lowest rates associated with peripherally inserted central catheters and highest rates with haemodialysis catheters. In febrile patients, the presence of an intravenous catheter should always prompt consideration of whether the line is the source, even if there is no exit site inflammation. If catheter-related infection appears likely, the line should be removed if possible. Either peripheral and line tip cultures, or timed cultures of blood drawn peripherally and through the line, should be taken. Empirical antibiotics should be aimed at S. aureus and aerobic Gram-negative organisms, and blood cultures should be repeated at 72 h. If S. aureus is grown, cure requires removal of the catheter, at least 14 days of parenteral therapy, and consideration of echocardiography (preferably transoesophageal). If the patient remains febrile for >72 h, blood cultures at 72 h grow S. aureus, or there is a prosthetic heart valve, the risk of endocarditis is high and 6 weeks of parenteral therapy should be given. Prevention requires an organized system of surveillance, with a strict policy on insertion of central lines in controlled conditions and regimented catheter care. The role of impregnated catheters in prevention remains controversial.

show abstract

“…Thirty-nine catheters were associated with a local in¬ fection: purulence developed at the catheter site in nine, 27 …”

Section: Catheter-related Infectionsmentioning

confidence: 99%

Low Infection Rate and Long Durability of Nontunneled Silastic Catheters

Raad¹

1993

Arch Intern Med

View full text Add to dashboard Cite

show abstract

Rapid Diagnosis of Intravascular Catheter-Related Sepsis

Cited by 43 publications

References 7 publications

A critical approach to the pathogenesis, diagnosis, treatment and prevention of catheter-related bloodstream infections and nosocomial endocarditis

A critical approach to the pathogenesis, diagnosis, treatment and prevention of catheter-related bloodstream infections and nosocomial endocarditis

Diagnosis and management of catheter‐related bloodstream infections due to Staphylococcus aureus

Low Infection Rate and Long Durability of Nontunneled Silastic Catheters

Contact Info

Product

Resources

About