2023
DOI: 10.1038/s43856-023-00305-w
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Rapid digital pathology of H&E-stained fresh human brain specimens as an alternative to frozen biopsy

Abstract: Background Hematoxylin and Eosin (H&E)-based frozen section (FS) pathology is presently the global standard for intraoperative tumor assessment (ITA). Preparation of frozen section is labor intensive, which might consume up-to 30 minutes, and is susceptible to freezing artifacts. An FS-alternative technique is thus necessary, which is sectioning-free, artifact-free, fast, accurate, and reliably deployable without machine learning and/or additional interpretation training. … Show more

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