Despite widespread interest in white-tailed deer (Odocoileus virginianus) in the southeastern United States, historical deer populations and densities have not been compiled into one accessible source. We digitized maps from 1950, 1970, 1982, and 2003 and reviewed literature to quantify population sizes and densities in the Southeast, although previous estimates may not be accurate. Deer population sizes declined to a minimum of <215,000 during the early 1900s. Population sizes and mean deer densities were 304,000 and 0.22 deer/km 2 by 1940, 476,000 and 0.35 deer/km 2 by 1950, 2.9 million to 4.1 million and 2.2 to 3.1 deer/km 2 by approximately 1970, 6.2 million and 4.6 deer/km 2 by 1982, and 10.8 million to 12 million and 8 to 9 deer/km 2 by about 2003. Although our estimates are likely not completely accurate in space and time, due to difficulty of counting animals, they provide the best available information and a range and trend in values, with general corroboration among sources. The current population size may be greater than during pre-Euro-American settlement, when based on minimum historical deer densities, or, conversely, the current population may be within the bounds of mid to high historical deer densities. Large deer densities trigger a research need to evaluate deer effects on vegetation, but threshold densities when deer are damaging to herbaceous plants may need to be reconsidered. Instead, we conjecture that deer may be considered a natural disturbance helpful in controlling increased tree densities during the past century, albeit placing a secondary stress upon declining herbaceous plants, which are losing ground to trees.