Rapid formation of ultrahigh strength vascular graft: Prolonging clotting time micro-dimension hollow vessels with interpenetrating polymer networks

Xu, Huilun; Liu, Kejun; Su, Yimeng; Liu, Zhengjiang; Yan, Wei; Hu, Yinchun; Zhao, Liqin; Chen, Lingfeng; Lian, Xiaojie; Huang, Di

doi:10.1016/j.compositesb.2022.110456

Cited by 8 publications

(1 citation statement)

References 49 publications

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“…Although the current artificial blood vessel transplantation is more mature. [ 1–3 ] However, bacterial infection due to the procedure is a major problem at present. [ 4 ] When an artificial blood vessel is implanted into body, microorganisms can reach the surface of the biomaterial and adhere to it.…”

Section: Introductionmentioning

confidence: 99%

Complexation‐Induced Resolution Enhancement Pleiotropic Small Diameter Vascular Constructs with Superior Antibacterial and Angiogenesis Properties

Liu

Yan

et al. 2023

Adv Healthcare Materials

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Abstract3D printing has been widely applied for preparing artificial blood vessels, which will bring innovation to cardiovascular disorder intervention. However, the printing resolution and anti‐infection properties of small‐diameter vessels (Φ < 6 mm) have been challenging in 3D printing. The primary objective of this research is to design a noval coaxial 3D printing post‐processing method for preparing small‐size blood vessels with improved antibacterial and angiogenesis properties. The coaxial printing resolution can be more conveniently improved. Negatively charged polyvinyl alcohol (PVA) and alginate (Alg) interpenetrating networks artificial vessels are immersed in positively charged chitosan (CTS) solution. Rapid dimensional shrinkage takes place on its outer surface through electrostatic interactions. The maximum shrinkage size of wall thickness can reach 61.2%. The vessels demonstrate strong antibacterial properties against Escherichia coli (98.8 ± 0.5%) and Staphylococcus aureus (97.6 ± 1.4%). In rat dorsal skin grafting experiments, Cu2+ can promote angiogenesis by regulating hypoxia‐inducible factor‐1 pathway. No artificial blood vessel blockage occur after 5 d of blood circulation in vitro.This article is protected by copyright. All rights reserved

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Section: Introductionmentioning

confidence: 99%

Complexation‐Induced Resolution Enhancement Pleiotropic Small Diameter Vascular Constructs with Superior Antibacterial and Angiogenesis Properties

Liu

Yan

et al. 2023

Adv Healthcare Materials

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A Review on 3D Printing Processes in Pharmaceutical Engineering and Tissue Engineering: Applications, Trends and Challenges

Wang,

Wang

et al. 2024

Adv Materials Technologies

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As a 3D rapid prototyping technology, 3D printing (3DP) technology has been widely applied in medical research, fabricating various medical devices or implants. With the development of biomaterials and cell‐related technologies, 3DP, especially bioprinting technology, is quietly bringing great changes and opportunities in the medical industry. Beyond surgical models, medical devices, and implants, traditional 3DP, cell‐based 3D bioprinting, and emerging 4D printing (4DP) have significantly aided in the advancement and manufacture of pharmaceuticals and biological alternatives for tissue engineering. It is envisioned that future healthcare systems, based on evolving 3DP technology and precision medicine, will deliver customized solutions that cater to the unique differences and needs of each patient. In this review work, several mainstream 3D bioprinting technologies are presented, with a focus on recent advances in 3DP for pharmaceutical engineering and important tissue engineering, including vascular and bone tissue engineering. Challenges and future prospects of 3DP for drug discovery, drug delivery systems, artificial blood vessels, vascular and bone tissue engineering scaffolds, and practical applications are also covered. Finally, the differences between 3DP and 4DP, as well as the advantages and disadvantages of different stimulus response mechanisms in 4DP and their potential applications are summarized.

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Biopolymer-based composites for tissue engineering applications: A basis for future opportunities

Zarrintaj

Seidi

Azarfam

et al. 2023

Composites Part B: Engineering

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Rapid formation of ultrahigh strength vascular graft: Prolonging clotting time micro-dimension hollow vessels with interpenetrating polymer networks

Cited by 8 publications

References 49 publications

Complexation‐Induced Resolution Enhancement Pleiotropic Small Diameter Vascular Constructs with Superior Antibacterial and Angiogenesis Properties

Complexation‐Induced Resolution Enhancement Pleiotropic Small Diameter Vascular Constructs with Superior Antibacterial and Angiogenesis Properties

A Review on 3D Printing Processes in Pharmaceutical Engineering and Tissue Engineering: Applications, Trends and Challenges

Biopolymer-based composites for tissue engineering applications: A basis for future opportunities

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