Mulberry is an important crop for the sericulture sector because they are the main source of nutrition for silkworms. Sericulture is the practice of raising silkworms to produce silk, which is a valuable and opulent textile in many industries. Mulberry is the primary food source for silkworms, hence the availability and quality of mulberry are crucial to the sericulture industry. Therefore, development of improved varieties is essential for enhancing silk production. Attempts were made to develop high yielding mulberry varieties with vigorous vegetative growth and early sprouting suitable for tropical agroclimatic regions through controlled pollination. The importance of developing a high-yielding variety with early sprouting is emphasized, as it can lead to increased silk production with improved profitability to farmers. The review also describes methods of controlled pollination, which are used to produce hybrid seeds with desired traits. The various factors that influence the success of controlled pollination, including timing, temperature, humidity, and nutrition, are discussed. Finally, the review summarizes the research on the development of high-yielding mulberry varieties with vigorous vegetative growth and early sprouting. Overall, the information provides valuable insights into the development of improved mulberry varieties for tropical regions and highlights the potential for increased silk production and profitability to farmers.