Rapid growing pulmonary cavernous lymphangioma after chronic process for ten years

Abstract

HighlightsPulmonary cavernous lymphangioma very rarely appears as a solid tumour.We encountered a case of pulmonary lymphangioma mimicking a malignant disease.Surgical resection of lymphangiomas is recommended for both diagnosis and treatment.

Rare Diagnosis of a Multilobular Pulmonary Mass

“…10 Only two cases underwent PET-CT imaging, including the current case, and both cases showed slight accumulation. 6 However, these findings are not sufficiently characteristic to reliably differentiate lymphangioma from non-small cell lung cancer, bronchogenic cyst, and hemangioma.…”

“…For this differential diagnosis, the detection of IHC markers is useful. 6 Among these, CD31, CD34, and podoplanin (detected by antibody D2-40) are widely used as markers of lymphangiomas, and a combination of these tests may increase the diagnostic accuracy. 5 CD31 and CD34 are relatively sensitive and specific markers of endothelial differentiation that are expressed in the majority of vascular tumors.…”

“…2 In terms of cavernous lymphangioma, only eight cases have been reported. [3][4][5][6][7][8] An analysis of the complete series, including the current one, indicated that patient ages ranged from 2 days to 59 years. The female-to-male ratio was 7:10.…”