Rapid hemostasis using a self-assembling peptide matrix for midprocedural bleeding in endoscopic sphincterotomy

Toyonaga, Haruka; Hayashi, Tsuyoshi; Hama, Kazuki; Nakamura, Ryô; Iwano, Kosuke; Takahashi, Kuniyuki; Katanuma, Akio

doi:10.1055/a-1960-3198

Cited by 6 publications

(5 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Risk factors of post‐EST hemorrhage include coagulopathy, anticoagulation within 3 days after ERCP, cholangitis, bleeding during EST, and ERCP at institutions with low case volume 2 . Options for achieving hemostasis after post‐EST hemorrhage include compression with balloon catheters, applying ice‐cold water or saline solution with epinephrine, injection of hypertonic saline and epinephrine, coagulation with hemostatic forceps, argon plasma coagulation, clipping, placement of covered self‐expandable metal stents, and a self‐assembling peptide matrix 1,3–5 . However, some of these methods may require specialized devices or complicated procedures and involve high costs.…”

Section: Brief Explanationmentioning

confidence: 99%

Hemostasis for postendoscopic sphincterotomy hemorrhage using a stone exaction balloon filled with ice‐cold water

Mie,

Nakagawa,

Sasaki

2024

Digestive Endoscopy

View full text Add to dashboard Cite

show abstract

Section: Brief Explanationmentioning

confidence: 99%

Hemostasis for postendoscopic sphincterotomy hemorrhage using a stone exaction balloon filled with ice‐cold water

Mie,

Nakagawa,

Sasaki

2024

Digestive Endoscopy

View full text Add to dashboard Cite

show abstract

“…In the GI field, numerous studies have shown that RDI is useful for the control of bleeding through improved visibility of the deep thick vessels 20 and bleeding points in hemorrhagic ulcers 21 , 22 and esophageal variceal rupture. 23 However, in the biliopancreatic area, only some case reports 24 , 25 , 26 are available and no large‐scale studies have been performed.…”

Section: Mechanisms and Equipment Of Ieementioning

confidence: 99%

Recent advancements in image‐enhanced endoscopy in the pancreatobiliary field

Toyonaga,

Hayashi,

Hama

et al. 2024

DEN Open

Self Cite

View full text Add to dashboard Cite

Image‐enhanced endoscopy (IEE) has advanced gastrointestinal disease diagnosis and treatment. Traditional white‐light imaging has limitations in detecting all gastrointestinal diseases, prompting the development of IEE. In this review, we explore the utility of IEE, including texture and color enhancement imaging and red dichromatic imaging, in pancreatobiliary (PB) diseases. IEE includes methods such as chromoendoscopy, optical‐digital, and digital methods. Chromoendoscopy, using dyes such as indigo carmine, aids in delineating lesions and structures, including pancreato‐/cholangio‐jejunal anastomoses. Optical‐digital methods such as narrow‐band imaging enhance mucosal details and vessel patterns, aiding in ampullary tumor evaluation and peroral cholangioscopy. Moreover, red dichromatic imaging with its specific color allocation, improves the visibility of thick blood vessels in deeper tissues and enhances bleeding points with different colors and see‐through effects, proving beneficial in managing bleeding complications post‐endoscopic sphincterotomy. Color enhancement imaging, a novel digital method, enhances tissue texture, brightness, and color, improving visualization of PB structures, such as PB orifices, anastomotic sites, ampullary tumors, and intraductal PB lesions. Advancements in IEE hold substantial potential in improving the accuracy of PB disease diagnosis and treatment. These innovative techniques offer advantages paving the way for enhanced clinical management of PB diseases. Further research is warranted to establish their standard clinical utility and explore new frontiers in PB disease management.

show abstract

“…Recently, a method for maintaining visibility during gastrointestinal bleeding involving the injection of a gel with an appropriate viscosity (Viscoclear; Otsuka Pharmaceutical Factory, Inc., Tokushima, Japan) was reported 2 3 . Additionally, the hemostatic effect of a self-assembling peptide gel (PuraStat; 3-D Matrix Europe SAS, Lyon, France) used during gastrointestinal endoscopic procedures has been reported 4 5 . Purastat is an aqueous peptide solution that becomes neutral upon contact with blood and body fluids, and its peptide molecules form fibers in solution to form a peptide hydrogel.…”

Section: Figmentioning

confidence: 99%

Enhancing visibility and hemostasis during necrosectomy for walled-off necrosis: the “dual-gel method”

Hama,

Toyonaga,

Ishii

et al. 2024

Endoscopy

Self Cite

View full text Add to dashboard Cite

Rapid hemostasis using a self-assembling peptide matrix for midprocedural bleeding in endoscopic sphincterotomy

Cited by 6 publications

References 5 publications

Hemostasis for postendoscopic sphincterotomy hemorrhage using a stone exaction balloon filled with ice‐cold water

Hemostasis for postendoscopic sphincterotomy hemorrhage using a stone exaction balloon filled with ice‐cold water

Recent advancements in image‐enhanced endoscopy in the pancreatobiliary field

Enhancing visibility and hemostasis during necrosectomy for walled-off necrosis: the “dual-gel method”

Contact Info

Product

Resources

About