Rapid identification and monitoring of cooking oil fume-based toxic volatile organic aldehydes in lung tissue for predicting exposure level and cancer risks

Prakasham, Karthikeyan; Gurrani, Swapnil; Wu, Chia-Fang; Wu, Ming-Tsang; Hsieh, Tusty-Jiuan; Peng, Chiung-Yu; Huang, Po-Chin; Krishnan, Anbarasu; Tsai, Pei-Chien; Lin, Yu-Chia; Tsai, Bongee; Lin, Yuan-Chung; Ponnusamy, Vinoth Kumar

doi:10.1016/j.chemosphere.2023.139704

Cited by 2 publications

(2 citation statements)

References 36 publications

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“…This variation could be attributed to the influence of chemical components present in COF particles on their physical properties, such as surface area and reactivity . These factors, in turn, affect the behavior of COF particles within the respiratory system and their potential to induce biological responses . Additionally, the specific health effects of gaseous COFs and their interactions with particulate COFs are still being studied.…”

Section: Resultsmentioning

confidence: 99%

“…51 These factors, in turn, affect the behavior of COF particles within the respiratory system and their potential to induce biological responses. 52 Additionally, the specific health effects of gaseous COFs and their interactions with particulate COFs are still being studied. Gaseous COFs can interact with the particles emitted by COFs through various mechanisms, including adsorption onto particle surfaces, chemical reactions, formation of coatings or layers on particle surfaces, and condensation of chemical compounds.…”

Section: Metabolic Profiling and Related Disturbed Metabolic Pathwaysmentioning

confidence: 99%

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Diverse Metabolic Effects of Cooking Oil Fume from Four Edible Oils on Human BEAS-2B Cells: Implications for Health Guidelines

Wang,

Liu,

Shi

et al. 2023

Environ. Sci. Technol.

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The 2021 WHO guidelines stress the importance of measuring ultrafine particles using particle number concentration (PNC) for health assessments. However, commonly used particle metrics such as aerodynamic diameter and number concentrations do not fully capture the diverse chemical makeup of complex particles. To address this issue, our study used high-throughput mass spectrometry to analyze the properties of cooking oil fumes (COFs) in real time and evaluate their impact on BEAS-2B cell metabolism. Results showed insignificant differences in COF number size distributions between soybean oil and olive oil (peak concentrations of 5.20 × 10 5 /cm 3 ), as well as between corn oil and peanut oil (peak concentrations of 4.35 × 10 5 /cm 3 ). Despite the similar major chemical components among the four COFs, variations in metabolic damage were observed, indicating that the relatively small amount of chemical components of COFs can also influence particle behavior within the respiratory system, thereby impacting biological responses. Additionally, interactions between accompanying gaseous COFs and particles may alter their chemical composition through various mechanisms, introducing additional chemicals and modifying existing proportions. Hence, the chemical composition and gaseous components of COFs hold equal importance to the particle number concentration (PNC) when assessing their impact on human health. The absence of these considerations in the current guidelines underscores a research gap. It is imperative to acknowledge that for a more comprehensive approach to safeguarding public health, guidelines must be regularly updated to reflect new scientific findings and robust epidemiological evidence.

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Section: Resultsmentioning

confidence: 99%

Section: Metabolic Profiling and Related Disturbed Metabolic Pathwaysmentioning

confidence: 99%

Diverse Metabolic Effects of Cooking Oil Fume from Four Edible Oils on Human BEAS-2B Cells: Implications for Health Guidelines

Wang,

Liu,

Shi

et al. 2023

Environ. Sci. Technol.

View full text Add to dashboard Cite

show abstract

Impact of air frying on food lipids: Oxidative evidence, current research, and insights into domestic mitigation by natural antioxidants

de Oliveira,

Viana,

Keller

et al. 2024

Trends in Food Science & Technology

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Rapid identification and monitoring of cooking oil fume-based toxic volatile organic aldehydes in lung tissue for predicting exposure level and cancer risks

Cited by 2 publications

References 36 publications

Diverse Metabolic Effects of Cooking Oil Fume from Four Edible Oils on Human BEAS-2B Cells: Implications for Health Guidelines

Diverse Metabolic Effects of Cooking Oil Fume from Four Edible Oils on Human BEAS-2B Cells: Implications for Health Guidelines

Impact of air frying on food lipids: Oxidative evidence, current research, and insights into domestic mitigation by natural antioxidants

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