Rapid immunoassay for dual-mode detection of HPV16 and HPV18 DNA based on Au@PdPt nanoparticles

Xiao, Huanxin; Chen, Weiguang; Lin, Mingxia; Jiang, Shilin; Cui, Xiping; Zhao, Suqing

doi:10.1039/d3ay02307a

Anal. Methods

2024

DOI: 10.1039/d3ay02307a

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Rapid immunoassay for dual-mode detection of HPV16 and HPV18 DNA based on Au@PdPt nanoparticles

Huanxin Xiao,

Weiguang Chen,

Mingxia Lin

et al.

Abstract: Cervical cancer (CC) remains one of the most severe global health challenges toward women primarily due to persistent infection with high-risk human papillomavirus (HPV) subtypes, particularly with HPV16 and HPV...

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Facile Synthesis of Trimetallic Hexoctahedral Au@PdPt Nanoparticles for Electrocatalytic Oxidation of Methanol

Bi,

Yin,

Wang

et al. 2024

J. Phys. Chem. C

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In this study, trimetallic Au@PdPt nanoparticles (NPs) were synthesized by a seed-mediated technique, possessing a hexoctahedral (HOH) Au core with a branched PdPt alloy shell. The fabrication process involved the synthesis of HOH Au NPs exhibiting high-index {651} facet as nanotemplates, followed by the epitaxial growth of Pd and Pt on these NPs to yield HOH Au@ PdPt NPs. The size and composition of HOH Au@PdPt NPs as well as the thickness of PdPt alloy shells (from 2 to 4, 5, and 8 nm) can be precisely adjusted by varying the quantity of Pd and Pt precursors. The catalytic efficacy of these Au@PdPt NPs was significantly enhanced through the synergistic effect between Au, Pd, and Pt, along with the increased contact areas afforded by multibranched PdPt alloy shells. For methanol electro-oxidation, the catalytic activity of HOH Au@PdPt NPs depends on the Pt content showing a distinctive volcano-type pattern. Remarkably, the HOH Au@Pd 0.3 Pt 0.3 NPs demonstrate optimum catalytic performance for methanol oxidation in acidic conditions, exhibiting superior electrocatalytic properties compared to commercial Pt black catalysts. Their ECSA value, mass, and specific activities are 47.21 m 2 g −1 , 0.93 A mg −1 , and 1.97 mA cm −2 , respectively. This research can be exploited to fabricate catalysts possessing exceptional properties by precisely designing and controlling the size, composition and morphology of the trimetallic Au@PdPt NPs.

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Facile Synthesis of Trimetallic Hexoctahedral Au@PdPt Nanoparticles for Electrocatalytic Oxidation of Methanol

Bi,

Yin,

Wang

et al. 2024

J. Phys. Chem. C

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show abstract

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Rapid immunoassay for dual-mode detection of HPV16 and HPV18 DNA based on Au@PdPt nanoparticles

Abstract: Cervical cancer (CC) remains one of the most severe global health challenges toward women primarily due to persistent infection with high-risk human papillomavirus (HPV) subtypes, particularly with HPV16 and HPV...

Cited by 1 publication

References 43 publications

Facile Synthesis of Trimetallic Hexoctahedral Au@PdPt Nanoparticles for Electrocatalytic Oxidation of Methanol

Facile Synthesis of Trimetallic Hexoctahedral Au@PdPt Nanoparticles for Electrocatalytic Oxidation of Methanol

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