2024
DOI: 10.1001/jamanetworkopen.2024.9744
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Rapid Initiation of Injection Naltrexone for Opioid Use Disorder

Matisyahu Shulman,
Miranda G. Greiner,
Hiwot M. Tafessu
et al.

Abstract: ImportanceInjectable extended-release (XR)-naltrexone is an effective treatment option for opioid use disorder (OUD), but the need to withdraw patients from opioid treatment prior to initiation is a barrier to implementation.ObjectiveTo compare the effectiveness of the standard procedure (SP) with the rapid procedure (RP) for XR-naltrexone initiation.Design, Setting, and ParticipantsThe Surmounting Withdrawal to Initiate Fast Treatment with Naltrexone study was an optimized stepped-wedge cluster randomized tri… Show more

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