The detection of growth promoter residues in meat requires rapid and sensitive methods for an effective screening before further confirmation with more expensive and time-consuming sophisticated instrumentation. The presence of these residues in meat would constitute a risk for consumers' health, and current European Directives establish the mechanisms for screening and confirmation of all these residues in foods of animal origin. The large amount of samples and the diversity of residues to be analyzed make easy, rapid, and sensitive analytical methodologies necessary for screening. This manuscript presents the developments in liquid chromatography for its use as screening technique and rapid detection of growth promoter residues in meat.