“…Its powder consists of a basic reagent (zinc oxide, 90%) and a retarding agent (magnesium oxide, 10%), while the liquid contains orthophosphoric acid, water and metal salts (105). An ionic reaction occurs between orthophosphoric acid and zinc oxide after manipulation, forming an amorphous mass with a low pH (106). However, due to its high solubility, an effective link between zinc phosphate cement and dentin is not achieved, leading to the chemical dissolution of the cement, followed by microleakage and an increased risk of recurrent caries (107,108).…”