Rapid-Onset Vancomycin-Induced Thrombocytopenia With Reexposure

Getz, Ted M.; Packer, Clifford D.

doi:10.1177/1060028019867433

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2019

2024

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Cited by 8 publications

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“…The onset of VIT has been reported to be between 7 and 10 days after the introduction of the drug. There were only a few cases described of VIT occurring within 24 h of administration of the drug if the patient was previously sensitized [5] . In this case report, our patient was treated with intravenous vancomycin for 9 days without any adverse reaction on initial admission.…”

Section: Discussionmentioning

confidence: 99%

Re-exposure causing rapid onset of vancomycin induced thrombocytopenia

Boodhai

Maharaj

Rodríguez

et al. 2022

IDCases

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Vancomycin is used for the treatment of gram-positive infections. The increasing prevalence of methicillin-resistant Staphylococcus aureus since the 1980 s has led to a significant increase in the clinical utility of vancomycin in the United States. The diagnosis of vancomycin induced thrombocytopenia (VIT) poses a challenge since it requires the exclusion of other etiologies of thrombocytopenia, such as infectious or immunologic diseases and alternative drugs. Physicians should be aware that VIT is a rare but important complication of IV vancomycin therapy and failure to recognize this diagnosis may lead to a delay in discontinuation of vancomycin and serious complications

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Section: Discussionmentioning

confidence: 99%