Rapid progression of mitral stenosis after atrial septal defect closure in a Lutembacher's syndrome patient

Abstract

The combination of the atrial septal defect (ASD) and mitral stenosis (MS) is an unusual clinical entity called Lutembacher's syndrome. The hemodynamic interaction between the two cardiac malformations modifies the disease progression of each other. The symptom and progression of MS were thought to be slowed because of the existence of a left‐to‐right shunt that relived the blood flow through the mitral orifice. There is no consensus about caring this patient population for now. Here, we present a 58‐year‐old female with mild MS and coexistent ASD experiencing rapid progression of mitral valve lesions after percutaneous ASD closure. This case might identify the effect of ASD on delaying MS progression. From this point of view, MS and coexisting ASD should be evaluated and treated as a whole.

A Case Series on Successful Surgical Management of Patients Presenting With Lutembacher’s Syndrome to a Tertiary Healthcare Center in Northern India

“…According to René Lutembacher (1916), "classical Lutembacher's syndrome" is a congenital ASD compounded by acquired MS [ 7 ]. Although Corvisart initially noted an association between ASD and MS in 1811, in Lutembacher's original report from 1916, when the patient was a 61-year-old woman who had given birth seven times, the ameliorating effect of the ASD on MS was clear.…”