Rapid Quantification of 4,4′-Methylenedianiline by Surface-Enhanced Raman Spectroscopy

Abstract

Methylenedianiline (MDA) is a common industrial chemical with health and product safety concerns. Common analysis methods require many steps including extraction and derivatization ending in GC/MS or HPLC analysis, which minimize its use as an on-line or at-line technique. The procedure can take hours, prohibiting its use as a real-time decision-making tool as well as using valuable resources and laboratory space. The new method presented here has been validated for MDA quantification in industrial grease samples over the concentration range of 1-40 ppm 4,4'-MDA. We present comparative results to the currently accepted method with excellent fidelity. This analytical method using surface-enhanced Raman spectroscopy reduces sample preparation and analysis time by more than an hour while preserving method accuracy, specificity, and dynamic range.

Quantification of Amines in Refinery Process Water via Surface-Enhanced Raman Spectroscopy

“…Raman spectroscopy can be amplified by the use of noble-metal nanoparticles. − These nanoparticles act as antennae, increasing the efficiency of Raman scattering by 3–9 orders of magnitude. This signal enhancement allows the detection of a wide variety of molecules down to trace concentrations. ,− Coined “surface-enhanced Raman spectroscopy” (SERS), this effect was first discovered in the 1970s and was conclusively demonstrated to be sensitive enough to observe the vibrations of a single molecule. ,, …”

Quantitative Analysis of Triazine-Based H2S Scavengers via Raman Spectroscopy

“…The intensity of the observed spectrum is linearly related to the concentration in solution . We use this relationship coupled with an internal standard to produce a fast, laboratory-quality test for MEA-triazine quantification in fresh scavenger solutions, which is an approach that has been used successfully for analyte quantitation in other complex sample matrices. , In recent years, because of the miniaturization of lasers, electronics, and microprocessors, Raman spectrometers have decreased in size, and cost, thereby increasing portability and convenience. This Research Note details the application of cutting-edge Raman techniques to create a rapid and accurate MEA-triazine monitoring system.…”