Rapid quantification of pharmaceuticals and pesticides in passive samplers using ultra high performance liquid chromatography coupled to high resolution mass spectrometry

Occurrence and distribution of pharmaceutically active and endocrine disrupting compounds in Singapore's marine environment: Influence of hydrodynamics and physical–chemical properties

“…Concentrations of carbamazepine in the coastal waters of Singapore from the present study (<0.3e10.9 ng/L) are comparable to what has been reported elsewhere in Europe and Japan (Magner et al, 2010;Nakada et al, 2008;Wille et al, 2010), but are an order of magnitude lower than what has been reported from the use of passive samplers in Belgium (Wille et al, 2011). Ibuprofen (<2.2e 9.1 ng/L) was in the lower range of what has been reported elsewhere in UK estuaries (Thomas and Hilton, 2004) and in Marina Bay in Singapore before it was transformed into a freshwater reservoir (Wu et al, 2010).…”

A multibiomarker approach to explore interactive effects of propranolol and fluoxetine in marine mussels

“…Our objective was to investigate possible adverse outcomes triggered by a combination of fluoxetine (FX), a selective serotonin reuptake inhibitor used in the treatment of depression and other mood disorders, and propranolol (PROP), a b-adrenergic receptor antagonist used to counteract cardiovascular pathologies (Weir, 2009). These compounds have been detected in coastal environments at concentrations in the range of 3e596 ng/L (FX; Vasskog et al, 2008;Benotti and Brownawell, 2007) and 0.3e6329 ng/L (PROP; Wille et al, 2011Wille et al, , 2010Yang et al, 2011) and also may be effectively bioaccumulated by mussels (Du et al, 2014a;Ericson et al, 2010;.…”

Screening of pharmaceuticals and illicit drugs in wastewater and surface waters of Spain and Italy by high resolution mass spectrometry using UHPLC-QTOF MS and LC-LTQ-Orbitrap MS

“…LTQ-Orbitrap is operated in data dependent acquisition (DDA) mode whereby MS and MS n spectra are obtained simultaneously, however the number of compounds able to be acquired is limited and therefore may require subsequent injections. Some studies have been made on the identification of organic pollutants in water by QTOF MS (Gómez et al, 2010;Gonzalez-Mariño et al, 2012;Hernández et al, 2011;Ibáñez et al, 2009) and LTQ Orbitrap MS (Kosma et al, 2014;Pinhancos et al, 2011;Wille et al, 2011).…”