Rapid Recovery from Acute Kidney Injury in a Patient with Metformin-associated Lactic Acidosis and Hypothermia

Mustafa, Esmat; Liu, Liwen; Lien, Yeong‐Hau H.

doi:10.1016/j.amjmed.2011.06.016

Cited by 6 publications

(2 citation statements)

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“…In another study conducted by Li Cavoli et al among 1014 renal patients, it was reported that acute renal failure accompanied by lactic acidosis was detected in 47 patients who used metformin for hyperglycemia control (10). In another case of metformin intoxication reported by Mustafa et al, acute renal failure with lactic acidosis and hypothermia was reported (11). In our case, there was an elevated lactate level in the blood gas obtained at the first presentation.…”

Section: Discussionsupporting

confidence: 49%

A Case Report of Metformin Related Lactic Acidosis

Akbaş

AKUFUK

YILMAZ

et al. 2023

Journal of Emergency Medicine Case Reports

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Metformin is an oral antidiabetic drug of the biguanide classused in type 2 diabetic patients with normal renal function. The mortality rate is high in cases of lactic acidos is developing in metformin intoxication. In the emergency department, metformin intoxication should be considered in the differential diagnosis of patients whouse metformin and have high anion gap metabolic acidosis (lactic acidosis). The most important and effective treatment with early diagnosis is correction of metabolic acidosis with hemodialysis or hemofiltration methods, bicarbonate treatment, adjustment of blood glucose level. Cardiovascular system support therapy significantly reduces morbidity/mortality. In this case report, we present the early diagnosis and successful treatment of a patient with lactic acidosis due to metformin intoxication.

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