Rapid Recovery of Postoperative Pulmonary Function in Patients With Lung Cancer and Influencing Factors

Abstract

Among malignant tumors, lung cancer has the highest morbidity and mortality worldwide. Surgery is the first-line treatment for early-stage lung cancers, and has gradually advanced from conventional open-chest surgery to video-assisted thoracic surgery (VATS). Additionally, increasingly smaller surgical incisions and less surgical trauma have resulted in reduced pulmonary function damage. Previous studies have found that the level of pulmonary function loss and recovery is significantly correlated with postoperative complications and the quality of life. Thus, an accurate assessment of the preoperative pulmonary function and effective rehabilitation of postoperative pulmonary function are highly important for patients undergoing lung surgery. In addition, pulmonary function assessment after pulmonary rehabilitation serves as an objective indicator of the postoperative pulmonary rehabilitation status and is crucial to facilitating pulmonary function recovery. Furthermore, a complete preoperative assessment and effective rehabilitation are especially critical in elderly patients with pulmonary tumors, poor basic physiological functions, comorbid lung diseases, and other underlying diseases. In this review, we summarize the clinical significance of pulmonary function assessment in patients undergoing lung cancer surgery, postoperative changes in pulmonary function, effective pulmonary function rehabilitation, and the influencing factors of pulmonary function rehabilitation.

Longitudinal changes in the volume of residual lung lobes after lobectomy for lung cancer: a retrospective cohort study

“…In this study, we only included patients who underwent VATS surgery, partly because over 95% of lung surgeries in our center were performed using thoracoscopy, and open surgery was more closely associated with patients’ specific conditions. On the other hand, Lung surgery with VATS spares more chest wall muscle, cause less surgical trauma and less respiratory muscle injury, than conventional open-chest surgery, and hence are more conducive to postoperative pulmonary function recovery 30 .…”

Preoperative Physical Dysfunction Characteristics and Influence Factors Among Elderly Patients with Early Lung Cancer: A Latent Class Analysis

“…28 The preoperative pulmonary functional status can have a substantial impact on the patient's prognosis and postoperative quality of life. 29 Preoperative pulmonary function training can enhance pulmonary ventilation and reduce pulmonary complications. 30 Polański et al found that patients with anxiety and depression had a significantly lower quality of life.…”

An analysis of residual lung volume changes after segmentectomy based on three-dimensional computed tomography

“…Third, only 3D-CT and pulmonary function tests, which mainly focus on lung air volume, were performed. In other words, indices such as pulmonary blood flow, oxygen uptake, and symptoms of patients, such as percutaneous oxygen saturation (SpO 2 ), partial pressure of arterial oxygen (PaO 2 ), diffusing capacity of lung for carbon monoxide (DLCO), and the 6-minute walking test ( 22 , 27 , 28 ). Furthermore, in the analysis of volumetric changes before and after surgery, as conducted in this study, where the residual lungs divided into several parts, investigations utilizing imaging techniques for a more detailed local volume analysis that reflects more functional lung volume assessments—such as these reported by previous studies with lung perfusion SPECT/CT, radiologic lung weight, and functional lung volume measurement for example excluding low attenuation area—were not undertaken in our research ( 10 , 11 , 19 , 29 , 30 ).…”