Rapid Reduction of Severe Asymptomatic Hypertension

Zeller, Kathleen R.; Kuhnert, La Von; Matthews, Carol

doi:10.1001/archinte.1989.00390100024007

Cited by 65 publications

(1 citation statement)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Sublingual nifedipine administered to inpatients with hypertensive urgencies has been associated with an increased incidence of ischemic neurovascular events, even after receiving small doses of medication that result in moderate BP reduction without resultant hypotension [ 27 , 28 ]. Beta-blockers (intravenous labetalol), angiotensin-converting enzyme inhibitors (e.g., captopril), and clonidine have also been implicated in treatment-related adverse events [ 29 , 30 ].…”

Section: Outcomes Associated With Treatment Of Inpatient Hypertensionmentioning

confidence: 99%

Treatment of Hypertension Among Non-Cardiac Hospitalized Patients

Chaganti

Lange

2022

Curr Cardiol Rep

View full text Add to dashboard Cite

Purpose of Review This review provides a contemporary perspective and approach for the treatment of hypertension (HTN) among patients hospitalized for non-cardiac reasons. Recent Findings Elevated blood pressure (BP) is a common dilemma encountered by physicians, but guidelines are lacking to assist providers in managing hospitalized patients with elevated BP. Inpatient HTN is common, and management remains challenging given the paucity of data and misperceptions among training and practicing physicians. The outcomes associated with intensifying BP treatment during hospitalization can be harmful, with little to no long-term benefits. Data also suggests that medication intensification at discharge is not associated with improved outpatient BP control. Summary Routine inpatient HTN control in the absence of end-organ damage has not shown to be helpful and may have deleterious effects. Since routine use of intravenous antihypertensives in hospitalized non-cardiac patients has been shown to prolong inpatient stay without benefits, their routine use should be avoided for inpatient HTN control. Future large-scale trials measuring clinical outcomes during prolonged follow-up may help to identify specific circumstances where inpatient HTN control may be beneficial.

show abstract

Section: Outcomes Associated With Treatment Of Inpatient Hypertensionmentioning

confidence: 99%

Treatment of Hypertension Among Non-Cardiac Hospitalized Patients

Chaganti

Lange

2022

Curr Cardiol Rep

View full text Add to dashboard Cite

show abstract

Acute Reduction of Blood Pressure in Asymptomatic Patients With Severe Hypertension

Fagan¹

1989

Arch Intern Med

View full text Add to dashboard Cite

Management of Hypertensive Crises

Gifford¹

1991

JAMA

107

View full text Add to dashboard Cite

The availability of potent antihypertensive drugs that will decrease markedly elevated blood pressure within minutes to hours has changed the concepts of definition and therapy of hypertensive emergencies and urgencies. Intravenous infusion of sodium nitroprusside can be used in the truly emergent situation and is effective, reliable, and safe. While oral therapy is more convenient, it is not as consistently effective as parenteral administration and can lead to excessive reductions in blood pressure that are more difficult to manage than when short-acting agents are given intravenously.

show abstract

Rapid Reduction of Severe Asymptomatic Hypertension

Cited by 65 publications

References 15 publications

Treatment of Hypertension Among Non-Cardiac Hospitalized Patients

Treatment of Hypertension Among Non-Cardiac Hospitalized Patients

Acute Reduction of Blood Pressure in Asymptomatic Patients With Severe Hypertension

Management of Hypertensive Crises

Contact Info

Product

Resources

About