Rapid sarcomatous transformation of an ameloblastic fibroma of the mandible: Case report and literature review

Kousar, Aisha; Hosein, Mervyn; Ahmed, Zubair; Minhas, Khurram

doi:10.1016/j.tripleo.2008.07.031

Cited by 30 publications

(22 citation statements)

References 13 publications

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“…21,22 Metastases have been reported in 2 of 72 cases; these 2 patients reportedly died with AFS, one of metastatic melanoma and the other of recurrence that did not respond to further treatment. 12,23 Chemotherapy has been used in cases showing recurrence. 11,24 In a review of the literature by Lai et al, 3 they reported a mortality rate of 25.4% for 69 reported cases.…”

Section: E6mentioning

confidence: 99%

Ameloblastic Fibrosarcoma of the Mandible: A Case Report and a Review of the Literature

Shetawi¹,

Alpert²,

Buchbinder³

et al. 2015

Journal of Oral and Maxillofacial Surgery

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Section: E6mentioning

confidence: 99%

Ameloblastic Fibrosarcoma of the Mandible: A Case Report and a Review of the Literature

Shetawi¹,

Alpert²,

Buchbinder³

et al. 2015

Journal of Oral and Maxillofacial Surgery

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“…3,7 Including this patient, 92 documented cases of AFS were found in the English-language literature, with just 3 of 92 metastatic lesion presentations. 8,9 Clinicopathologic diagnosis at the first presentation is very important to distinguish AF from AFS, which can have a tremendous impact on prognosis and management.…”

Section: Discussionmentioning

confidence: 99%

Ameloblastic Fibrosarcoma of the Mandible With Distant Metastases

Pourdanesh

Mohamadi

Moshref

et al. 2015

Journal of Oral and Maxillofacial Surgery

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“…(4-6,9-13,16-113). Papers describing clinicopathological features similar to those described for AFS were included in the first instance (4,5,(9)(10)(11)(12)(13)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(28)(29)(30)32,(34)(35)(36)(37)(38)(39)42,43,(67)(68)(69)(70)(71)(72)(74)(75)(76)(77)(78)(79)(80)(81)(82)(83)(84)(85)(86)(87)(88)(89)91,…”

Section: Systematic Literature Reviewmentioning

confidence: 99%

Ameloblastic Fibrosarcoma: A Case Report and Literature Review

et al. 2017

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Here is described a case of ameloblastic fibrosarcoma (AFS) affecting the posterior mandible of a woman who was treated surgically and recovered without signs of recurrence or metastasis after 12 years of follow-up. Tumor sections were immunostained for cell cycle, epithelial and mesenchymal markers. Immunohistochemical analysis evidenced high Ki-67 positivity in stromal cells (mean of 20.9 cells/High power field). Epithelial cells displayed strong positivity for p53, p63 and cytokeratin 19. In addition to the case report, a systematic review of current knowledge is presented on the AFS's clinical-demographic features and prognostic factors. Based on the review, 88/99 cases were diagnosed as AFS, 9/99 as ameloblastic fibro-odontosarcoma and 2/99 as ameloblastic fibrodentinosarcoma. All these lesions displayed very similar clinical-demographic and prognostic features. Moreover, the review provided evidence that first treatment, regional metastasis, distant metastasis and local recurrence were significant prognostic values for malignant odontogenic mesenchymal lesions. Based on the findings, segregation among ameloblastic fibrosarcoma, ameloblastic fibrodentinosarcoma and ameloblastic fibro-odontosarcoma seems illogical, considering all these lesions have similar predilections and outcomes.

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Rapid sarcomatous transformation of an ameloblastic fibroma of the mandible: Case report and literature review

Cited by 30 publications

References 13 publications

Ameloblastic Fibrosarcoma of the Mandible: A Case Report and a Review of the Literature

Ameloblastic Fibrosarcoma of the Mandible: A Case Report and a Review of the Literature

Ameloblastic Fibrosarcoma of the Mandible With Distant Metastases

Ameloblastic Fibrosarcoma: A Case Report and Literature Review

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