Rapid SARS-CoV-2 disinfection on distant surfaces with UV-C: The inactivation is affected by the type of material

Olagüe, Cristina; Mitxelena-Iribarren, Oihane; Sierra-García, J.Enrique; Rodriguez-Merino, Fernando; Maestro, Sheila; Pérez-Lorenzo, E.; Guillén-Grima, Francisco; González‐Aseguinolaza, Gloria; Arana, Sergio; Smerdou, Cristian

doi:10.1016/j.jpap.2022.100138

Cited by 7 publications

(2 citation statements)

References 27 publications

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“…In every case, apart from MDF, elimination of viral particles of over 90% was confirmed, while for MDF, it was 19.9%. The time of exposure to UVC radiation was from 42 to 340 s [26].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the Efficacy of UV-C Radiation in Eliminating Microorganisms of Special Epidemiological Importance from Touch Surfaces under Laboratory Conditions and in the Hospital Environment

Różańska,

Walkowicz,

Bulanda

et al. 2023

Healthcare

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Introduction: Healthcare-associated infections in the post-pandemic era are as important as they were before COVID-19. The dominant route of transmission of microorganisms in health care units is the contact route, for which hand hygiene is of cardinal importance, but also effective disinfection of touch surfaces. Traditional disinfection based on chemical compounds is sensitive to human errors. Therefore, a valuable supplement to it can be contactless disinfection methods, including the use of UV-C. The aim of the study was to assess the effectiveness of UV-C radiation in eliminating selected, most important pathogens of particular epidemic importance from surfaces made of various materials: stainless steel, plastic and glass, most often found in hospital conditions. Material and Method: In laboratory conditions, the study was conducted using bacterial strains of great epidemiological importance and Candida auris. In hospital wards, samples were taken before and after disinfection for comparisons of the composition and quantity of bacteria. In laboratory conditions, carriers made of steel, plastic and glass were contaminated with a bacterial suspension with a density of approx. 0.5 McFarland, and then the density of persistent microorganisms was assessed after 10 min of UV-C irradiation. Results: The high effectiveness of UV-C radiation in eliminating bacteria contaminating touch surfaces in hospital wards and in laboratory conditions has been confirmed. The elimination efficiency in laboratory conditions was slightly lower (statistically insignificant) on the plastic surface, which is probably related to subtle differences in the thickness of the contaminating layer. Hydrophobic properties and the smallest suspension diameter were confirmed for the tested plastic carriers. Conclusions: UV-C disinfection is a desirable element to support traditional, chemical methods of disinfection in hospital conditions, effective against multidrug-resistant bacteria and C. auris.

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“…In every case, apart from MDF, elimination of viral particles of over 90% was confirmed, while for MDF, it was 19.9%. The time of exposure to UVC radiation was from 42 to 340 s [26].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the Efficacy of UV-C Radiation in Eliminating Microorganisms of Special Epidemiological Importance from Touch Surfaces under Laboratory Conditions and in the Hospital Environment

Różańska,

Walkowicz,

Bulanda

et al. 2023

Healthcare

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“…An enhanced understanding of the role of closed communal environments as a source of SARS‐CoV‐2 transmission has focused attention on the importance of environmental cleaning and disinfection as a means of reducing disease spread. Established techniques for whole‐room decontamination of public environments such as ultraviolet radiation has demonstrated sufficient efficacy toward the disinfection of SARS‐CoV‐2 ( 12 , 13 , 14 , 15 ); however, they are broadly limited to infrequent use in unoccupied and sealed environments due to their harmful radiation effects and long‐term material degradation upon repeated exposure ( 16 , 17 ). Consequently, novel methods of environmental decontamination to augment current SARS‐CoV‐2 infection control procedures are continuously being sought.…”

Section: Introductionmentioning

confidence: 99%

Viricidal Efficacy of a 405‐nm Environmental Decontamination System for Inactivation of Bacteriophage Phi6: Surrogate for SARS‐CoV‐2

Sinclair

Ilieva

Morris

et al. 2023

Photochem & Photobiology

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The highly transmittable nature of SARS-CoV-2 has increased the necessity for novel strategies to safely decontaminate public areas. This study investigates the efficacy of a low irradiance 405-nm light environmental decontamination system for the inactivation of bacteriophage phi6 as a surrogate for SARS-CoV-2. Bacteriophage phi6 was exposed to increasing doses of low irradiance (~0.5 mW cm À2 ) 405nm light while suspended in SM buffer and artificial human saliva at low (~10 3-4 PFU mL À1 ) and high (~10 7-8 PFU mL À1 ) seeding densities, to determine system efficacy for SARS-CoV-2 inactivation and establish the influence of biologically relevant suspension media on viral susceptibility. Complete/near-complete (≥99.4%) inactivation was demonstrated in all cases, with significantly enhanced reductions observed in biologically relevant media (P < 0.05). Doses of 43.2 and 172.8 J cm À2 were required to achieve ~3 log 10 reductions at low density, and 97.2 and 259.2 J cm À2 achieved ~6 log 10 reductions at high density, in saliva and SM buffer, respectively: 2.6-4 times less dose was required when suspended in saliva compared to SM buffer. Comparative exposure to higher irradiance (~50 mW cm À2 ) 405-nm light indicated that, on a per unit dose basis, 0.5 mW cm À2 treatments were capable of achieving up to 5.8 greater log 10 reductions with up to 28-fold greater germicidal efficiency than that of 50 mW cm À2 treatments. These findings establish the efficacy of low irradiance 405-nm light systems for inactivation of a SARS-CoV-2 surrogate and demonstrate the significant enhancement in susceptibility when suspended in saliva, which is a major vector in COVID-19 transmission.

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Tailoring the mechanical and rheological properties of poly(lactic acid) by sterilizing UV-C irradiation

Virág,

Tóth,

Polyák

et al. 2024

International Journal of Biological Macromolecules

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Rapid SARS-CoV-2 disinfection on distant surfaces with UV-C: The inactivation is affected by the type of material

Cited by 7 publications

References 27 publications

Evaluation of the Efficacy of UV-C Radiation in Eliminating Microorganisms of Special Epidemiological Importance from Touch Surfaces under Laboratory Conditions and in the Hospital Environment

Evaluation of the Efficacy of UV-C Radiation in Eliminating Microorganisms of Special Epidemiological Importance from Touch Surfaces under Laboratory Conditions and in the Hospital Environment

Viricidal Efficacy of a 405‐nm Environmental Decontamination System for Inactivation of Bacteriophage Phi6: Surrogate for SARS‐CoV‐2

Tailoring the mechanical and rheological properties of poly(lactic acid) by sterilizing UV-C irradiation

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