Rapid Shallow Breathing (Frequency-Tidal Volume Ratio) Did Not Predict Extubation Outcome

The Prediction of Extubation Success of Postoperative Neurosurgical Patients Using Frequency–Tidal Volume Ratios

“…However, they evaluated a heterogeneous population. Subsequent studies showed that the different results observed for the relation of f/V t ratio and extubation success was mainly related to the point in time of the extubation process, the test was applied and to the kind of patients evaluated [3,5,8,13,18,20,26,32,34].…”

“…Multiple weaning parameters have been investigated as possible predictors of extubation outcome and studies have shown that they are not accurate predictors [18,[27][28][29][39][40][41][42]. On the basis of the difficulty to find predictors of failure extubation, few studies have been reported, however, that link the relationship between preoperative/ intraoperative characteristics and postoperative extubation outcome [43][44][45].…”

“…Several studies [12][13][14][15][16][17][18][19][20] have addressed objective criteria to predict weaning from mechanical ventilation in the intensive care unit. Attention has now moved toward redefining the decision of patient extubation, as 10-20% of extubations may still fail and require reintubation [21][22][23][24][25].…”

Protocol-directed weaning from mechanical ventilation: clinical outcome in patients randomized for a 30-min or 120-min trial with pressure support ventilation

“…Single weaning parameters used to predict extubation success [1,2,3] seem to have a rather low accuracy [2,4], and some of them may even have a low negative predictive value [4]. Moreover, authors still disagree about the validity of standard respiratory functional variables determined prior to weaning and supposed to represent prediction criteria for a successful extubation [5,6,7,8]. Therefore recent prospective and randomized protocol-directed weaning studies have assessed weaning readiness by means of a structured evaluation [5,9,10,11,12,13].…”

Effects of noninvasive positive pressure ventilatory support in non-COPD patients with acute respiratory insufficiency after early extubation

“…However, the incidence of weaning failure is still high and amounts to approximately 20 % in different studies [5,7,8]. A major cause of weaning failure is acute respiratory failure due to respiratory muscle fatigue or increased work of breathing due to decreased pulmonary compliance or increased resistance [3].…”