Rapid, simple and green solid phase extraction based on polyaniline nanofibers-mat for detecting non-steroidal anti-inflammatory drug residues in animal-origin food

Emerging Applications of Versatile Polyaniline-Based Polymers in the Food Industry

“…Solid-phase extraction (SPE) with a PANI/PAC nanofibre mat was used in the extraction of NSAIDs, as the amino and benzene ring groups of PANI rendered it a strong affinity towards NSAIDs via a hydrogen bond, π–π interaction, its acid–base function, and its hydrophobicity ( Figure 10 ). This showed practical feasibility with meat and egg samples and was able to detect a wide array of NSAIDs (ibuprofen, naproxen, diclofenac, carprofen, ketoprofen, tolfenamic acid, and salicylic acid) with LODs and recoveries in the ranges of 0.6–12.2 µg kg −1 and 85.18–107.31%, respectively [ 152 ]. Other similar studies on the extraction of NSAIDs using PANI have also been done in recent years ( Table 4 ) [ 153 , 154 , 155 ].…”

Current Strategies for Studying the Natural and Synthetic Bioactive Compounds in Food by Chromatographic Separation Techniques

“…Several papers created during the last two years [35][36][37][38][39][40][41] demonstrate the importance of different CLC procedures to determine selected veterinary drugs in animal food and food products belonging to various groups including non-steroidal anti-inflammatory agents (NSAIDS), some antibiotics, and others according to EU Commission Decision 2002/657/EC requirements [35] to guarantee food safety.…”

“…Whereas, LC-MS/MS methods with triple quadrupole (TQ), electrospray ionization (ESI) in multiple reaction monitoring (MRM) mode have been used for the determination of multiclass NSAIDs in meat of swine, chicken, eggs, and bovine [37,38,40]. Developed chiral UHPLC-TQ-ESI-MS/MS in MRM mode have been successfully applied to the simultaneous determination of four profens enantiomers including naproxen, carprofen, indoprofen, and flurbiprofen in fish tissues [39].…”