Rapidly increasing prevalence of eosinophilic oesophagitis in Western Australia

Cherian, Sarah; Smith, Nicholas M.; Forbes, David

doi:10.1136/adc.2006.100974

Cited by 219 publications

(170 citation statements)

References 29 publications

Supporting

Mentioning

142

Contrasting

Unclassified

Order By: Relevance

“…Numerous prevalence studies have been performed around the globe, both in pediatric and adult populations, documenting a prevalence of between 0.002% and 6.5% [Prasad et al 2009;Veerappam et al 2009;Ronkainen et al 2007;Cherian et al 2006;Straumann and Simon, 2005;Noel et al 2004]. A more recent study by Prasad and colleagues showed a prevalence of 15% in patients with a complaint of dysphagia [Prasad et al 2007].…”

Section: Background and Aimsmentioning

confidence: 99%

Routine screening for eosinophilic esophagitis in patients presenting with dysphagia

Ricker

McNear

Cassidy

et al. 2010

Therap Adv Gastroenterol

View full text Add to dashboard Cite

Abstract:Background: Eosinophilic esophagitis (EoE) is a clinicopathologic disorder first described in 1978 which has gained significant recognition over the past 10 years. Numerous prevalence studies have been performed around the globe, both in pediatric and adult populations documenting a prevalence between 0.002% and 6.5%. The aim of this study is to assess the utility of routinely screening for EoE in patients with dysphagia. Methods: A prospective, observational study in which adult patients with a complaint of esophageal dysphagia were enrolled. Results: Of the 135 patients enrolled, 122 completed the study; 100 patients had nonobstructive dysphagia, while 22 patients had a luminal finding which could explain their dysphagia. The prevalence of EoE in the nonobstructive dysphagia group was 22% (95% CI: 13.930.1%); 32.7% of male patients with nonobstructive dysphagia were found to have EoE compared with 8.9% of females (p ¼ 0.004). The mean age of nonobstructive patients found to have EoE was 37.8 years. White patients with nonobstructive dysphagia were found to have a 25.9% prevalence of EoE, compared with 0% of African Americans, 0% of Asians, and 14.3% of Hispanics. When comparing Whites with non-Whites, the prevalence of EoE was noted to be 25.9% versus 5.3%, respectively (p ¼ 0.050). Conclusions: EoE is a common cause of nonobstructive dysphagia. We believe that the high prevalence of EoE in patients with nonobstructive dysphagia supports the practice of routine biopsies to screen for the presence of abnormally high numbers of eosinophils in this subgroup.

show abstract

Section: Background and Aimsmentioning

confidence: 99%

Routine screening for eosinophilic esophagitis in patients presenting with dysphagia

Ricker

McNear

Cassidy

et al. 2010

Therap Adv Gastroenterol

View full text Add to dashboard Cite

show abstract

“…Leslie et al (2) reported the prevalence of EE to be 4% among 250 children with CD and in this study 3 of 10 children were reported to have symptoms of CD and EE, esophagus appeared normal at endoscopy, but biopsies showed evidence of EE similar to our case. Another study showed that approximately 30% of children diagnosed as having EE had normal-appearing esophageal mucosa at endoscopy (6). Our patient presented with only abdominal pain and constipation.…”

Section: Discussionmentioning

confidence: 93%

Çölyak hastalığı ve eozinofilik özefajit birlikteliği: Bu iki hastalık için bir tesadüf mü?

Appak¹,

Ayhan²,

Kasırga³

2015

Ege Tıp Dergisi

View full text Add to dashboard Cite

Celiac disease and eosinophilic esophagitis are usually considered to be separate gastrointestinal diseases; however, it appears that they may coexist more often than would be expected. We report the case of a 5-year-old girl who had positive celiac serology and was assessed as having type 3c celiac disease according to the Marsh classification with endoscopic pathology. However, the patient's eosinophils were more than 100 per high-power field in esophageal mucosal biopsy specimens and she was evaluated as having eosinophilic esophagitis as well. The relationship between celiac disease and eosinophilic esophagitis is not clear. Nevertheless, coexistence of eosinophilic esophagitis needs to be considered in children with celiac disease.

show abstract

“…Noel et al demonstrated that the incidence of the disease in Cincinnati, OH, was 10 out of 100,000 children and the prevalence was 43 out of 100,000 [2]. In Australia, the incidence of primary EE increased from 0.05 to 0.89 out of 10,000 between 1995 and 2004 [3]. Nevertheless, it is unknown if this rise is due to a real incidence increase or just better diagnosis.…”

Section: Introductionmentioning

confidence: 99%

Dysphagia and Eosinophilic Infiltration of the Esophageal Muscular Layer: A Case Report

Plaz

Natale

et al. 2014

J Med Cases

View full text Add to dashboard Cite

Eosinophilic gastrointestinal diseases are a group of pathological entities characterized by an eosinophilic infiltration of the gastrointestinal tract without known cause. Eosinophilic esophagitis (EE) is one of these conditions, which has three diagnostic criteria: symptoms of esophageal dysfunction, mucosal infiltration of 15 eosinophils per high-power field (HPF) microscope and no response to high-dose proton pump inhibitors (PPIs). A 51-year-old patient attended to the emergency department claiming to suffer from heartburn, dysphagia, regurgitation and chest pain. He was treated with high doses of PPIs without success and the condition progressed to food impaction. An esophagogram, which showed esophageal motor dysfunction in the middle and lower part of the esophagus, was performed, and pathologic examination of an esophageal biopsy taken by endoscopy revealed histopathological changes suggestive of gastroesophageal reflux disease. An esophageal manometry was carried out and it reported diffuse esophageal spasms and a hypertensive inferior esophageal sphincter with incomplete relaxation. A Heller cardiomyotomy was performed and the biopsy specimen revealed fibrosis and eosinophilic infiltration of the muscular layer. Symptoms ceased for 6 months after which symptoms reappeared. The patient was diagnosed with EE and treated with budesonide orally 12 mg/day with complete remission of all symptoms. In this peculiar case, the eosinophilic infiltration was in the muscular layer of the esophagus, not in the mucosa; therefore, it did not meet the diagnostic criteria of EE nor its differential diagnoses. Nevertheless, treatment with oral steroids was in fact effective.

show abstract

Rapidly increasing prevalence of eosinophilic oesophagitis in Western Australia

Cited by 219 publications

References 29 publications

Routine screening for eosinophilic esophagitis in patients presenting with dysphagia

Routine screening for eosinophilic esophagitis in patients presenting with dysphagia

Çölyak hastalığı ve eozinofilik özefajit birlikteliği: Bu iki hastalık için bir tesadüf mü?

Dysphagia and Eosinophilic Infiltration of the Esophageal Muscular Layer: A Case Report

Contact Info

Product

Resources

About