2021
DOI: 10.1016/j.eucr.2021.101771
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Rapidly recurrent prostatic obstruction due to granulomatosis with polyangiitis

Abstract: Granulomatosis with polyangiitis (GPA) is a rare cause of prostatitis. Our case illustrates a case of granulomatous prostatitis secondary to unrecognised GPA requiring multiple surgical interventions. The patient presented with lower urinary tract symptoms. They underwent two endoscopic prostatic resections for recurrent urinary obstruction due to granulomatous prostatitis before a diagnosis of GPA was made. The rarity of this pathology, challenges in making a diagnosis and the systemic nature of this disease … Show more

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Cited by 2 publications
(2 citation statements)
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“…The patient did not develop side effects due to cyclophosphamide such hemorrhagic cystitis, which may be confused with urological GPA relapse. 5 Some presentations of GPA relapse with clinical manifestations as dysuria or hematuria, must be distinguishable of from cyclophosphamide long-terms side effects. 2 Careful follow-up and monitoring of basic laboratory tests (regularly complete blood cell counts and urinalysis with urinary sediment testing) may prevent adverse effects of this treatment and minimize their impact.…”
Section: Discussionmentioning
confidence: 99%
“…The patient did not develop side effects due to cyclophosphamide such hemorrhagic cystitis, which may be confused with urological GPA relapse. 5 Some presentations of GPA relapse with clinical manifestations as dysuria or hematuria, must be distinguishable of from cyclophosphamide long-terms side effects. 2 Careful follow-up and monitoring of basic laboratory tests (regularly complete blood cell counts and urinalysis with urinary sediment testing) may prevent adverse effects of this treatment and minimize their impact.…”
Section: Discussionmentioning
confidence: 99%
“…Prostatitis is reported in about 12-37% of patients with urogenital involvement of GPA. GPA can involve the prostate gland causing acute obstruction with the potential to recur rapidly after surgical treatment [35]. Testicular vasculitis is observed in up to 36% of patients [34].…”
Section: Anca-associated Vasculitides Granulomatosis With Polyangiitis (Gpa)mentioning
confidence: 99%