Rare Association of Congenital Bicuspid Aortic Valve, Annuloaortic Ectasia, and Anomalous Origin of Left Circumflex Coronary Artery

Takahashia, b Masafumi; Ikedab, Uichi; Shimadab, Kazuyuki; Takedaa, Hisanao

doi:10.1159/000176329

Cited by 6 publications

(3 citation statements)

References 9 publications

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“…3 CAD in young adults usually occurs in patients with multiple predisposing risk factors. In the absence of predisposing risk factors, coronary ectasia has been described as an isolated congenital lesion, or in association with syphilis, congenital heart disease, 4 scleroderma, polyarteritis nodosa, and, particularly, mucocutaneous lymph node syndrome (Kawasaki disease). 5,6 Our patient developed extensive 2-vessel disease at a very early age.…”

Section: Discussionmentioning

confidence: 99%

“…Coronary artery ectasia (CAE) is an uncommon disorder diagnosed in 0.3% to 4% of patients undergoing coronary angiography. [1][2][3] CAE has been reported in association with a variety of pathological conditions, such as syphilis, congenital heart disease, 4 scleroderma, polyarteritis nodosa, and, particularly, mucocutaneous lymph node syndrome (Kawasaki disease). 5,6 CAE is usually considered a variant of atherosclerotic coronary artery disease.…”

Section: Introductionmentioning

confidence: 99%

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Rare Association of Diffused Coronary Ectasia and Anomalous Origin of Left Circumflex Coronary Artery in a Man with Heterozygous Familial Hypercholesterolemia

et al. 2005

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Coronary artery ectasia (CAE) is an uncommon form of coronary artery disease. It has been reported in association with a variety of pathological conditions, such as isolated congenital heart disease and Kawasaki disease. CAE is more relevant in young adults with multiple predisposing risk factors, especially familial hypercholesterolemia, and is usually considered a form of atherosclerotic coronary artery disease. A case of CAE is reported with familial hypercholesterolemia and diffuse ectasia of the coronary vessels in association with anomalous origin of the left circumflex coronary artery, which lacked ectatic segments. This combination has not been reported previously.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Rare Association of Diffused Coronary Ectasia and Anomalous Origin of Left Circumflex Coronary Artery in a Man with Heterozygous Familial Hypercholesterolemia

et al. 2005

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“…These variations from the usual coronary artery anatomy may be part of the developmental abnormalities responsible for BAVs. 19 Anomalous origins of the right 20 , 21 and left 22 coronary arteries, association with annuloaortic ectasia, and anomalous origins of the left circumflex coronary artery 23 and single left coronary artery, 24 have been noted in patients with BAVs. Spontaneous coronary artery dissection may occur in BAV patients.…”

Section: Coronary Artery Disordersmentioning

confidence: 99%

The bicuspid aortic valve and related disorders

Yuan

Hua

2010

Sao Paulo Med. J.

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Bicuspid aortic valve (BAV) is the most common congenital cardiac malformation, affecting 1-2% of the population, with strong male predominance. Individuals may have a normally functioning BAV, and may be unaware of its presence and the potential risk of complications. However, they may easily develop aortic valve disorders: either stenotic or regurgitant, or both. Today, BAV is recognized as a syndrome incorporating aortic valve disorders and aortic wall abnormalities, including aortic dilation, dissection or rupture. Congenital or hereditary diseases such as ventricular septal defect, patent ductus arteriosus, coarctation of the aorta, Turner's syndrome, Marfan's syndrome etc., may frequently be associated with BAV. Infective endocarditis and occasionally thrombus formation may develop during the lives of BAV patients. Elevated cholesterol or C-reactive protein may be seen in laboratory findings of these patients. Beta-blockers and statins are the possibilities for medical treatment, and aortic valve repair/replacement and ascending aorta replacement are indicated for patients with a severely diseased aortic valve and aorta. Rigorous follow-up throughout life is mandatory after BAV has been diagnosed. The aim of the present article was to describe the implications of BAV and its associated disorders, and to discuss diagnostic and treatment strategies. RESUMOA válvula aórtica bicúspide (VAB) é a malformação cardíaca congênita, mais comum afetando 1-2% da população, com forte predominância no sexo masculino. Indivíduos afetados podem exibir funcionamento normal da VAB, ignorando sua presença e o potencial risco de complicações associadas.Mas podem facilmente desenvolver disfunções de valva aórtica, com estenose, regurgitação, ou ambas. Hoje em dia, a VAB é reconhecida como uma síndrome incorporando alterações de valva aórtica e anormalidades da parede aórtica, inclusive dilação da aorta, dissecção ou ruptura. Doenças congênitas ou hereditárias, como defeito do septo ventricular, canal arterial patente, coartação de aorta, síndrome de Turner, síndrome de Marfan etc., podem estar frequentemente associadas com VAB. A endocardite infecciosa e ocasionalmente formação de trombo podem se desenvolver durante a vida nos pacientes com VAB. Elevação do colesterol ou proteína C-reativa pode ser observada nos resultados laboratoriais desses pacientes.Betabloqueador e estatinas são as opções de tratamento médico e reparação/substituição da valva aórtica e substituição da aorta ascendente são indicadas para pacientes com doença grave da valva aórtica e artéria aorta. Acompanhamento rigoroso por toda a vida é obrigatório quando do diagnóstico da VAB. O objetivo do presente artigo é descrever as implicações do VAB assim como suas desordens associadas e discutir as estratégias de diagnóstico e tratamento.

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The Bicuspid Aortic Valve

Braverman¹,

Beardslee²

2009

Valvular Heart Disease: A Companion to Braunwald's Heart Disease

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Rare Association of Congenital Bicuspid Aortic Valve, Annuloaortic Ectasia, and Anomalous Origin of Left Circumflex Coronary Artery

Cited by 6 publications

References 9 publications

Rare Association of Diffused Coronary Ectasia and Anomalous Origin of Left Circumflex Coronary Artery in a Man with Heterozygous Familial Hypercholesterolemia

Rare Association of Diffused Coronary Ectasia and Anomalous Origin of Left Circumflex Coronary Artery in a Man with Heterozygous Familial Hypercholesterolemia

The bicuspid aortic valve and related disorders

The Bicuspid Aortic Valve

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