Rare Case: 70 Year Old Patient with Seronegative Lupus Nephritis

Dağel, Tuncay; Meram, Ece; Önal, Emine Meltem; Erbil, Damla; Bülbül, Mustafa Cem; Uysal, Sanem Pinar

doi:10.5222/mmj.2018.34467

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2023

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“…SLE is associated with different types of antibodies including antinuclear antibodies (ANA), anti-double stranded DNA (anti-dsDNA), atiplasma membrane antibodies, and anti-smith antibodies. ANA is diagnostic for SLE and found positive in 95% of the cases [10,11]. It was reported that only 50% of SLE cases to be positive for anti-dsDNA antibodies [12].…”

Section: Introduction Backgroundmentioning

confidence: 99%

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A young female with hypocomplementemic urticarial vasculitis associated with a rare CNS manifestation

et al. 2023

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This case report represents a rare case of 14-year-old female who diagnosed with hypocompementemic urticarial vasculitis syndrome that presents with glomerulonephritis, diffuse alveolar hemorrhage, and acute disseminated encephalomyelitis. The progression of the symptoms explained in the text below in which the final diagnosis was reached after a challenging approach. Patient was managed properly and followed up after treating with rituximab, although she represents no sign of the disease after a total of two cycles.

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Section: Introduction Backgroundmentioning

confidence: 99%

“…It was reported that only 50% of SLE cases to be positive for anti-dsDNA antibodies [12]. Few patients present with negative SLE serology [10,11]. Acute disseminated encephalomyelitis (ADEM) is an autoimmune disease characterized by demyelination in the brain, spinal cord, and occasionally the optic nerve.…”

Section: Introduction Backgroundmentioning

confidence: 99%