Rare case of huge vulvar angiomyofibroblastoma in a young female

Anggraeni, Tricia Dewi; Nuranna, Laila; Luthfiyanto, Muhammad; Siregar, Nuryati Chairani; Hellyanti, Tantri; Siregar, Trifonia Pingkan; Alexandra, Leonardo

doi:10.1016/j.gore.2021.100751

Cited by 5 publications

(11 citation statements)

References 9 publications

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“…The age of our patient was 57 years. However, it can occur in young females as well reported in the literature by Angraenni TD, et al in which a young female of 22 years, nulliparous presented with a painless vulvar mass slowly growing over a period of 10 years that was treated by wide excision [1]. The patient was followed over a period of 2 years and no recurrence was noted.…”

Section: Discussionmentioning

confidence: 75%

“…This was a case series of 10 patients with angiomyofibroblastoma [6]. The average age of females with angiomyofibroblastoma is between 30 to 50 years [1,3]. The age of our patient was 57 years.…”

Section: Discussionmentioning

confidence: 98%

“…Mesenchymal tumours of the vulva are a rare entity characterized by two main types i.e, benign angiomyofibroblastoma, and aggressive angiomyxoma. Both of them are difficult to diagnose and differentiate due to the rarity and overlapping gross morphological characteristics, histopathology, and immunohistochemistry features [1,2]. Angiomyofibroblastoma is the benign variant characterized by myofibroblastic cells and stromal cell differentiation and proliferation [3].…”

Section: Introductionmentioning

confidence: 99%

“…The treatment of the benign variant is wide local excision with lower recurrence rates after complete resection. But the angiomyxoma required deeper resection followed by radiotherapy, depending upon the depth of involvement [1].…”

Section: Introductionmentioning

confidence: 99%

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Recurrent vulval angiomyofibroblastoma; An unusual benign mesenchymal tumour, misdiagnosed

Sadiq¹

2022

J Clin Images Med Case Rep

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We present a case report of a middle aged post menopausal female with a huge pelvic mass for last 15 years that was previously misdiagnosed as chronic dermatitis. Based on its uncanny appearance, it was decided to do complete excision of the vulval mass to rule out any soft tissue tumour. The histopathology came out to be a rare benign lesion i.e, angiomyofibroblastoma with the immunohistochemistry report favouring the diagnosis. The patient after complete excision is under routine follow up and survelliance and is recurrence free to date.

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Section: Discussionmentioning

confidence: 75%

Section: Discussionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Recurrent vulval angiomyofibroblastoma; An unusual benign mesenchymal tumour, misdiagnosed

Sadiq¹

2022

J Clin Images Med Case Rep

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“…Angiomixomas agresivos tienen una inmunohistoquímica parecida y su diagnóstico diferencial radica tanto en una historia clínica detallada, en un examen físico minucioso y en un estudio histopatológico e inmunohistoquímico que descarten infiltraciones en tejidos adyacentes. La ausencia de expresión de receptores Bcl-2 no descarta el diagnóstico ya mencionado ya que dichos tumores si bien lo expresan en su mayoría de casos, no lo hacen en el 100%de las veces 18 .…”

Section: Tanto Los Angiomiofibroblastomas Como Losunclassified

Angiomiofibroblastoma vulvar. Un tumor vulvar poco común. A propósito de un caso

Castillo

Balseca

et al. 2022

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El Angiomiofibroblastoma es un tumor benigno de origen mesenquimatoso de baja incidencia, descrito por primera vez en 1992. Su localización mas común es en el tracto genital inferior femenino, especialmente en la vulva, aunque puede presentarse en distintas localizaciones tanto en hombres como mujeres. Entre los diagnósticos diferenciales se encuentran varios tumores vulvares dentro de los cuales se puede destacar el Angiomixoma agresivo el cual es de especial importancia descartarlo a la hora de planificar el tratamiento. Para esto se puede realizar estudios inmunohistoquímicos, los cuales de ser sugestivos del diagnóstico evidencian receptores positivos para Estrógenos y Progesterona, para Desmina, α –SMA, Vimentin, Bcl-2 y ausencia de receptores para S-100. El tratamiento definitivo se basa en la escisión quirúrgica de la lesión el cual no requiere bordes ampliados, a diferencia de cuando se trata del Angiofibroma agresivo que requiere una ampliación de la incisión debido a su alta capacidad de invasión local de este tumor.

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Angiomyofibroblastoma as a rare cause of vulvar mass: A case report and literature review

Einafshar,

Shari’at Moghani,

Radboy

et al. 2023

Clinical Case Reports

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Key Clinical MessageAngiomyofibroblastoma is a benign soft tissue tumor and a form of genital stromal mesenchymal tumor that primarily affects the vulva. It could possibly affect the reproductive‐aged women's lower genital tract (vagina).AbstractAngiomyofibroblastoma is a rare benign soft tissue tumor primarily affecting the vulva in reproductive‐aged women. We report a 67‐year‐old female complaining of a painless mass in her right vulva spreading to the right inguinal region over the past 2 years. The first clinical impression was a canal of Nuck hernia, diagnostic laparoscopy was planned to rule hernia out. The vulvar mass was excised, and a histopathology examination revealed Angiomyofibroblastoma.

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Rare case of huge vulvar angiomyofibroblastoma in a young female

Abstract: Highlights Huge angiomyofibroblastoma of the Vulva. Differential diagnosis between vulvar angiomyofibroblastoma and vulvar aggressive angiomyxoma. Comprehensive approach diagnosing and therapy of vulvar angiomyofibroblastoma.

Cited by 5 publications

References 9 publications

Recurrent vulval angiomyofibroblastoma; An unusual benign mesenchymal tumour, misdiagnosed

Recurrent vulval angiomyofibroblastoma; An unusual benign mesenchymal tumour, misdiagnosed

Angiomiofibroblastoma vulvar. Un tumor vulvar poco común. A propósito de un caso

Angiomyofibroblastoma as a rare cause of vulvar mass: A case report and literature review

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