Rare case of invasive lobular breast cancer metastasis to the endometrium

Abstract

Metastases to the female genital tract from extra-genital primary cancers are uncommon and usually occur during widespread metastatic disease. Breast cancers are the most frequent primaries, predominantly the lobular type. Here, we report a case of a 55-year-old woman with breast cancer endometrial metastasis who presented with postmenopausal vaginal bleeding. We highlight the importance of endometrial sampling to confirm the diagnosis and distinguish primary from metastatic cancer of the endometrium since the treatment and prognosis of these conditions are entirely different.

Uterine Metastasis from Carcinoma of Breast – A Systematic Analysis

“…In this study, the case reported by Muñoz-Iglesias et al [14] had no uterine symptoms, but the progressive elevation of tumor markers after 6 years of management of bilateral lobular carcinoma of the breast led to PET-CT and the discovery of uterine metastasis. In the cases reported by Thouvenot et al [34], D'souza et al [6], and Danolić et al [45] , PET-CT revealed widespread metastatic lesions.…”