Rare cause of recurrent urticaria in childhood and its unusual presentation: Solitary mastocytoma on vulva

Yılmaz, Ebru; Orhan, Dıclehan; Andıran, Fatih; Soyer, Özge

doi:10.1111/1346-8138.13454

Cited by 3 publications

(1 citation statement)

References 4 publications

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“…Mastocytomas may exhibit systemic symptoms and manifest in various body parts, exemplified by a case of vulval mastocytoma presenting with recurrent urticaria, emphasizing the importance of comprehensive physical examination, including examination of genital skin [ 7 ]. Further case reports document unusual histological features, such as mastocytoma with features of granuloma faciale (such as grenz zone, dermal telangiectasia and mixed inflammatory infiltrate) [ 8 ], pseudo carcinomatous hyperplasia and scattered eosinophils [ 9 ], eosinophilic infiltrate and flame figures, resembling histological features of Wells syndrome [ 10 ], hypervascular pseudo angiomatous histopathology, and xanthelasmoid clinical appearance [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

Large Congenital Cutaneous Mastocytoma Presenting With Recurrent Persistent Blistering: A Case Report

Cernova,

Patel,

Ligaj

et al. 2023

Cureus

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Congenital cutaneous mastocytoma is an uncommon disorder characterized by abnormal proliferation of mast cells. It typically presents as a single, small, yellowish-brown plaque, and its diagnosis is generally facilitated by distinctive clinical features, including a positive Darrier's sign. This report presents a case of an unusually large, solitary congenital mastocytoma encompassing nearly the entire circumference of the calf, observed in a newborn boy of Bangladeshi origin. Measuring 13x6 cm, the lesion formed large bullae and subsequent erosions. The perplexing clinical appearance prompted a skin biopsy, revealing monomorphic CD117 (c-KIT) positive infiltration without significant cell pleomorphism, confirming the diagnosis of cutaneous mastocytoma. The patient underwent management with potent and very potent topical steroids, oral antihistamines, and non-adhesive dressings, remaining under long-term follow-up with secondary care dermatology. In reporting this case, our objective is to augment the existing scientific literature by providing additional evidence that cutaneous mastocytomas can display a spectrum of clinical presentations, as illustrated in this case.

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Section: Discussionmentioning

confidence: 99%

Large Congenital Cutaneous Mastocytoma Presenting With Recurrent Persistent Blistering: A Case Report

Cernova,

Patel,

Ligaj

et al. 2023

Cureus

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Vulvar Nodules: A Rare Presentation of Mastocytosis

Lawson

Mir

Wilson

2018

Journal of Pediatric and Adolescent Gynecology

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Solitary cutaneous mastocytoma on the scalp of a child; a case report and review of literature

Bahadoram

Joonaki

Yaghoobi

et al. 2022

Voprosy gematologii/onkologii i immunopatologii v pediatrii

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Mastocytomas are solitary mast cell tumors that are generally seen on the trunk and extremities. Childhood-onset mastocytomas of the scalp are extremely rare. We report a case of a one-and-a-half-year-old toddler boy that presented with a yellow-brown plaque on his scalp. Pathological evaluation s revealed mast cell accumulation in the upper dermis. These cells were uniform with a fried-egg appearance and had visible cytoplasmic granules with Wright-Giemsa staining. This study demonstrates the difficulty of diagnosing soli¬tary mastocytomas as it is a very rare disease and has non-specific clinical findings. In this study, a child with a rare solitary cutaneous mastocytoma on the scalp was evaluated and a review of previous literature was conducted.

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Rare cause of recurrent urticaria in childhood and its unusual presentation: Solitary mastocytoma on vulva

Cited by 3 publications

References 4 publications

Large Congenital Cutaneous Mastocytoma Presenting With Recurrent Persistent Blistering: A Case Report

Large Congenital Cutaneous Mastocytoma Presenting With Recurrent Persistent Blistering: A Case Report

Vulvar Nodules: A Rare Presentation of Mastocytosis

Solitary cutaneous mastocytoma on the scalp of a child; a case report and review of literature

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