Rare fibrosing granulomatous mediastinitis of tuberculosis with involvement of the transverse sinus

Zhang, Chong; Yao, Minhua; Yu, Zhikai; Jiang, Lijun; Jiang, Xiaoying; Ni, Yiming

doi:10.1016/j.jtcvs.2006.11.023

Cited by 11 publications

(10 citation statements)

References 3 publications

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“…Of the single case reports where FM is specifically believed to be related to prior TB infection, presentations were due to superior vena cava syndrome,10 11 bronchial obstruction,12 pulmonary artery compression,13 as well as impingement of the transverse sinus and its adjacent vascular structures 14…”

Section: Case Presentationmentioning

confidence: 99%

“…However, interestingly they reported that her symptoms had not recurred at follow-up at time of publication. Zhang and colleagues removed a fibrotic mass, which encroached onto the aorta, pulmonary artery and left atrium, followed by anti-TB drugs, with good resolution of symptoms, although the length of follow-up was not specified 14. Despite compression of vascular structures, collateral circulation often develops over time and without acute obstruction, Baikoussis et al decided to monitor rather than intervene 10…”

Section: Case Presentationmentioning

confidence: 99%

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Post-tuberculous fibrosing mediastinitis: a review of the literature

Jarvis

Howard

et al. 2017

BMJ Open Resp Res

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Fibrosing mediastinitis (FM) is a rare disease where there is thickening of the fibrous tissue in the mediastinum. While histoplasmosis is the the most common recognised cause, the link with tuberculosis (TB) has been rarely documented. We review the link between TB and FM, and describe a case of probable TB-related FM.Our case is of a 74-year-old man who presented with breathlessness 3 years after fully treated TB. Scans revealed a calcified soft tissue mass within the mediastinum, and a diagnosis of fibrosing mediastinitis resulting in pulmonary hypertension was made. Tests for histoplasmosis and IgG4 staining were negative. Surgical intervention was not felt to be beneficial, and he was treated with prednisolone and mycophenolate mofetil.In the review, we highlight the two forms of mediastinitis—granulomatous versus fibrous, and how these two entities may be on a spectrum of disease progression. We also explore the prevalence, clinical presentation, pathogenesis, imaging techniques and treatment options of TB-related FM.

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Section: Case Presentationmentioning

confidence: 99%

Section: Case Presentationmentioning

confidence: 99%

Post-tuberculous fibrosing mediastinitis: a review of the literature

Jarvis

Howard

et al. 2017

BMJ Open Resp Res

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“…In the actual era of antituberculous chemotherapy there are only few cases reported in the recent Englishlanguage literature 3,4 .…”

Section: Case Reportmentioning

confidence: 99%

“…Diagnosis of tuberculous mediastinitis is often difficult: the clinical presentation lacks specificity and imaging studies do not provide conclusive information 3,4 . Though clinical presentation of our patient was acute, it seemed not immediately lifethreatening as usually observed in mediastinitis of other etiologies.…”

Section: Case Reportmentioning

confidence: 99%

Mediastinal tuberculosis: An unusual clinical presentation

Chafik

Benjelloun

Abdelghani

et al. 2010

Indian J Thorac Cardiovasc Surg

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The described case is of a 43-year-old man who presented with fever, severe dysphagia and dyspnea. Computed tomography scan revealed several mediastinal inhomogeneous masses. A multiloculated pleural effusion was also present. The patient underwent right thoracotomy, debridement of pleural cavity, opening of mediastinal pleura and evacuation of several multiloculated abscesses. Postoperative course was uneventful. Culture of samples taken at operation grew M. tuberculosis fully drug sensitive. Outcome was fully satisfactory. This report shows an unusual presentation of mediastinal tuberculosis. (Ind J Thorac Cardiovasc Surg 2010; 26: 38-40)

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“…Der fibrosierende Prozess im Mediastinum kann auch durch den Befall von Koronararterien zu einer myokardialen Ischämie führen [21,29].…”

Section: Klinische Präsentationunclassified