“…In addition, while targeted injections allow to dissect tissue‐specific functions (Moody, 2018), the use of chemical inhibitors as well as activators can serve to modulate signaling pathways at specific time points (Maj et al, 2016). Together with the technical means of rescue experiments, Xenopus is thereby ideally suited for the efficient and inexpensive analysis of candidate genes or genetic variants with a potential role in human disease (Bajpai et al, 2010; Devotta, Juraver‐Geslin, Gonzalez, Hong, & Saint‐Jeannet, 2016; Duncan & Khokha, 2016; Lienkamp, 2016; Martens et al, 2020; Ott et al, 2019; Pratt & Khakhalin, 2013; Schwenty‐Lara et al, 2020; Ufartes et al, 2018; Vivante et al, 2017).…”