Rare Malignant Skin Tumors

Eccrine Porocarcinoma: A Case Report of a Rare Skin Malignancy (Dermatopathologic View)

“…It typically appears in elderly people in the fifth to seventh decades of their life [4,10,13] with a slight preponderance among women [4]. The most common location is the lower extremity [4,13]. Our case is in accord with those clinical features.…”

“…EP exhibits no special features and it cannot be clinically distinguish from other common skin tumors [4,10]. It typically appears in elderly people in the fifth to seventh decades of their life [4,10,13] with a slight preponderance among women [4]. The most common location is the lower extremity [4,13].…”

“…Our case is in accord with those clinical features. EP is histogenetically derived from the dermal ducts of sweat glands and acrosyringium [13]. It usually consists of cohesive nests and islands of predominantly poroid basophilic tumor cells, that grow out from the epidermis, and (in case of invasive lesion) invade into the dermis and deeper tissue [4,13,14].…”

“…EP is histogenetically derived from the dermal ducts of sweat glands and acrosyringium [13]. It usually consists of cohesive nests and islands of predominantly poroid basophilic tumor cells, that grow out from the epidermis, and (in case of invasive lesion) invade into the dermis and deeper tissue [4,13,14]. The signs of ductal differentiation in the form of either well-formed atypical ducts or inconspicuous intracytoplasmic vacuoles are usually seen [4,13,14].…”

“…It usually consists of cohesive nests and islands of predominantly poroid basophilic tumor cells, that grow out from the epidermis, and (in case of invasive lesion) invade into the dermis and deeper tissue [4,13,14]. The signs of ductal differentiation in the form of either well-formed atypical ducts or inconspicuous intracytoplasmic vacuoles are usually seen [4,13,14]. However, the spectrum of histomorphological features may be heterogeneous comprising the clear-cell, squamous-cell and spindlecell differentiation lines, the presence of cuticular cells with eosinophilic cytoplasm, mucin-containing cells, or colonized melanocytes [4,13,14].…”