Rare pseudotumors of the urinary bladder in childhood

Abstract

We report two cases of inflammatory pseudotumors of the urinary bladder, one case of a chronic granulomatous pseudotumor (CGT) and one case of a pseudosarcomatous myofibroblastic (fibromyxoid) tumor (PMT). Both tumors resembled malignancies such as rhabdomyosarcomas regarding clinical appearance and imaging findings and represent rare urinary bladder tumors. The imaging findings on unenhanced and contrast-enhanced MRI as well as histological specimen are presented. Final diagnosis was made following elective surgery. Differential diagnosis of urinary bladder tumors as well as the imaging findings of these clinically comparable cases are discussed. Awareness of these benign lesions may prevent patients from inappropriate therapies such as chemotherapy or radiation therapy.

Inflammatory myofibroblastic tumour: an imaging dilemma (2010: 5b)

“…In children, IMFT may clinically mimic and even pathologically resemble rhabdomyosarcoma [1][2][3]. The radiological appearances of inflammatory pseudotumour are also nonspecific and can mimic more malignant counterparts [1,2,4]. Kim [5] reported a similar case of IMFT in the bladder, which appeared as a broad-based enhancing centrally necrotic mass involving the bladder wall with perivascular extension to other pelvic structures.…”

Coexistence of inflammatory pseudotumour and pseudomembranous cystitis: a histopathological surprise

“…IP is characterised histologically by the presence of acute and chronic inflammatory cells with a variable fibrous response. The radiological appearance of inflammatory pseudotumour is non-specific and cannot be easily differentiated from a malignant neoplasm 7 8…”

Effect of electron donors on 1,3‐butadiene polymerization by a Ziegler–Natta catalyst based on neodymium

“…Despite having a more benign clinical course, the aggressive appearance of IMFT might resemble other more malignant entities. In children, IMFT may clinically mimic and even pathologically resemble rhabdomyosarcoma 3–5; however, diagnosis can be confirmed histologically by routine light microscopy or even immunohistochemistry and electron microscopy when the former is deficient.…”