Rare skeletal muscle metastasis from renal cell carcinoma: case report and review of the literature

Salman, Rida; Sebaaly, Mikhael Georges; Asmar, Karl; Nasserdine, Mohammad; Bannoura, Sami; Khoury, Nabil

doi:10.1007/s13730-018-0350-1

Cited by 6 publications

(3 citation statements)

References 10 publications

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“…RCC is commonly known to metastasize to the lungs, bone, and brain, but RCC can metastasize to some atypical sites as well, such as skeletal muscle [4], scalp [5] and uvula [6], as described in the literature. This report describes the metastasis of clear cell renal cell carcinoma to the metatarsus.…”

Section: Discussionmentioning

confidence: 99%

Metatarsal metastasis from clear cell renal cell carcinoma: a case report and literature review

Han

Zhang

et al. 2020

BMC Urol

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Background: Bone metastasis is known to occur in some patients with cancer, usually in the spine, pelvis or ribs, and less than 0.01% of patients have metastases in the foot bone, so metatarsal metastasis is quite rare. The initial symptoms of osseous metastases are swelling, pain, or both. Case presentation: We report a 68-year-old man with solitary metatarsal metastasis 26 months after a diagnosis of renal clear cell carcinoma. The patient suffered intermittent swelling of his right foot and pain for one year due to trauma and was not treated. The doctor attributed the symptoms to trauma, administering massage therapy and a plaster cast to the patient at the local clinic. After reviewing the medical records, we found that this patient had a history of clear cell renal cell carcinoma. The patient underwent radiological examination and open biopsy of the first metatarsal bone of the right foot. These findings confirmed that the patient had a metatarsal metastasis from clear cell renal cell carcinoma. The patient subsequently underwent right foot amputation. No local recurrence or distant metastasis was found after a 6-month follow-up. Conclusion: Clinicians should be aware of a history of renal cell carcinoma (RCC) and fully understand the patient's past medical history. When treating patients with clear cell renal cell carcinoma who have unresolving bony pain or swelling, clinicians should always keep in mind the possibility of bone metastasis of RCC.

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Section: Discussionmentioning

confidence: 99%

Metatarsal metastasis from clear cell renal cell carcinoma: a case report and literature review

Han

Zhang

et al. 2020

BMC Urol

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“…Late metastasis of an RCC in soft tissues of the thigh has also been reported [ 12 ]. Rare cases of skeletal muscle metastasis from RCC have also been reported [ 13 , 14 , 15 , 16 ].…”

Section: Discussionmentioning

confidence: 99%

Late Metastasis of Renal Cell Carcinoma in Distal Femur Treated with Knee Joint Preservation: A Case Report

Choudhury¹,

Verma²,

Dhyani³

et al. 2022

JOCR

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“…Researchers have found that most common tumors with muscle metastases come from the thyroid, esophagus, stomach, pancreas, colon, rectum, bladder, breast, ovary, and prostate[ 7 - 10 ]. However, the most common sites of muscle metastases are the erector spine, iliopsoas, and paravertebral muscle[ 11 - 13 ], which are rare in skeletal muscles of limbs. Guidi et al [ 14 ] reported a case of epithelial cell carcinoma in the bladder, metastasizing into the superficial flexor muscle of the thumb, while, Katafigiotis et al [ 15 ] reported two cases of sartorius metastatic tumors.…”

Section: Discussionmentioning

confidence: 99%

Skeletal muscle metastases of hepatocellular carcinoma: A case report and literature review

Song¹,

Sun²,

Wu³

et al. 2021

WJCC

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BACKGROUND The metastasis of liver cancer to skeletal muscle is extremely rare compared to other sites. We herein report a case of rapidly developing skeletal metastases following liver transplantation due to primary liver cancer. CASE SUMMARY A 70-year-old male with underlying chronic hepatitis B virus infection was diagnosed with hepatocellular carcinoma (HCC), for which he underwent liver transplantation in 2014. Six years after receiving the transplant, pathological examination confirmed the presence of HCC without vascular invasion. He was admitted to the hospital with a rapidly growing mass on his right thigh. Ultrasound examination revealed a mixed echo mass in the lateral soft tissue of the middle part of the right femur. Magnetic resonance imaging showed heterogeneous iso-signal intensity on T1-weighted images and heterogeneous hyper-intensity on T2-weighted images compared to the surrounding muscles. Pathological examination of the ultrasound-guided needle biopsy specimen revealed that it was similar to the previously detected liver cancer; the diagnosis was metastasis of HCC. Surgical excision was performed. There were no other sites of metastasis, and the patient recovered well after surgery. CONCLUSION This report presents a rare case of skeletal metastasis following liver transplantation for HCC. The study suggests a possible role for skeletal muscle metastasis mechanisms, which should be the focus of future research.

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Rare skeletal muscle metastasis from renal cell carcinoma: case report and review of the literature

Cited by 6 publications

References 10 publications

Metatarsal metastasis from clear cell renal cell carcinoma: a case report and literature review

Metatarsal metastasis from clear cell renal cell carcinoma: a case report and literature review

Late Metastasis of Renal Cell Carcinoma in Distal Femur Treated with Knee Joint Preservation: A Case Report

Skeletal muscle metastases of hepatocellular carcinoma: A case report and literature review

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