Rare Vulvar Angiomyofibroblastoma: Case Series and Literature Review

Abstract

Background Angiomyofibroblastoma (AMFB) is an uncommon disease with few literature reports, leading to the poor understanding of its diagnosis, treatment, and postoperative follow-up plans among gynecologists. Objective To study the clinical and pathological features of vulvar AMFB and discuss its treatment and prognosis. Case Summary The 3 cases were characterized by a gradually increasing painless mass in the vulva. Preoperative diagnosis was difficult and mainly depended on ultrasonic examination. Immunohistochemistry confirmed clear boundaries of AMFB. This condition could be completely cured by surgery, and the prognosis was good. Conclusion The vulvar AMFB is a rare tumor that is frequently misdiagnosed before surgery. Ultrasound is preferred in auxiliary diagnosis, and surgery remains the best treatment, and long-term follow-up is necessary to avoid recurrence or other complications.

Angiomyofibroblastoma as a rare cause of vulvar mass: A case report and literature review

“…Currently, no drugs are available to treat AMF, and surgery is preferred. 16,25 It might be worth noting that AMF has a slight chance of recurrence or spreading. 5,11,26 Regarding the unknown and different characteristics of vulvar AMF, opinions, and clinical approaches are controversial.…”

“…The definitive diagnosis is finally confirmed by postoperative pathological examination. Currently, no drugs are available to treat AMF, and surgery is preferred 16,25 . It might be worth noting that AMF has a slight chance of recurrence or spreading 5,11,26 …”

“…Currently, no drugs are available to treat AMF, and surgery is preferred. 16 , 25 It might be worth noting that AMF has a slight chance of recurrence or spreading. 5 , 11 , 26 …”