Rate of a Click Chemistry reaction under catalysis by trace‐amounts of copper as evaluated by NMR spectroscopy

Nebbioso, Antonio; Mazzei, Pierluigi

doi:10.1002/mrc.4491

Cited by 3 publications

(3 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As shown in Figure S4, the conversion of both monomers in the click reaction leads to a decrease in the intensity of monomer signals and the appearance of new peaks. Specifically, peaks at 4.64 and 4.00 were attributed to the adjoining protons of the newly formed triazole ring . Based on this mechanism, the LbL assembly started with PAA-PEG 2 -Azi on substrates treated with piranha solution followed by the addition of PAA-Alk with the existence of Cu(I).…”

Section: Results and Discussionmentioning

confidence: 97%

“…Specifically, peaks at 4.64 and 4.00 were attributed to the adjoining protons of the newly formed triazole ring. 35 Based on this mechanism, the LbL assembly started with PAA-PEG 2 -Azi on substrates treated with piranha solution followed by the addition of PAA-Alk with the existence of Cu(I). During this process, the formation of triazole occurs together with a simultaneous attachment of the PAA-Alk layer to the underlying PAA-PEG 2 -Azi layer.…”

Section: Fabrication Of Fully Negatively Charged (Fnc) Lbl Nanofilmsmentioning

confidence: 99%

See 1 more Smart Citation

Fabrication of Fully Negatively Charged Layer-by-Layer Nanofilms with pH-Induced Remarkable Swelling–Shrinking Properties

Zhang,

Zeng,

et al. 2024

Chem. Mater.

View full text Add to dashboard Cite

Layer-by-layer (LbL) assembly by polyelectrolytes (PE) with opposite charges has been widely used for nanofilm fabrications with diverse functionalities. However, in a typical PE LbL assembly, the charges distributed along the polymer chains are used, resulting in the retention of charges only on the outermost layer. If the charges residing within the inner layers could be harnessed, then we could obtain nanofilms full of charge. Herein, we present a novel approach by employing click moiety-functionalized poly(acrylic acid) (PAA) to achieve LbL nanofilms with preserved charges. The film assembly was driven by copper-catalyzed azide–alkyne cycloaddition (CuAAC), thereby yielding fully negatively charged (FNC) nanofilms possessing unique properties compared to conventional PE nanofilms, including high stability over a wide pH range (pH 2–12) and reversible pH-induced remarkable swelling–shrinking properties in response to cyclic transitions between alkaline and acidic conditions. The swelling induced by the increase in pH reached 201% with a thickness change from 138 (pH 2) to 278 (pH 12) nm. AFM measurements showed distinct morphological changes for nanofilms post-treated by solutions with different pH values, and structure colors depending on pH were observed. This kind of FNC nanofilm holds high potential for application as a diagnostic nanomaterial such as positively charged ions and molecules in biomedical and environmental fields.

show abstract

Section: Results and Discussionmentioning

confidence: 97%

Section: Fabrication Of Fully Negatively Charged (Fnc) Lbl Nanofilmsmentioning

confidence: 99%

Fabrication of Fully Negatively Charged Layer-by-Layer Nanofilms with pH-Induced Remarkable Swelling–Shrinking Properties

Zhang,

Zeng,

et al. 2024

Chem. Mater.

View full text Add to dashboard Cite

show abstract

“…The first evidence of the reaction's occurrence was the immediate quenching of the methylene proton signal next to alkyne groups at 4.25 ppm due to the rapid complexation with Cu(I) 27 (Figure S6). Furthermore, the conversion of the azide groups led to a decrease in the intensity of -CH 2 -N 3 (peak q) and the appearance of new proton signals that were assigned to the adjoining protons next to the triazole rings 28 (peaks o and p) (Figure 1b). The reagents' peaks showed a decreasing trend with reaction time, while the triazole's peaks displayed the opposite behavior (Figure 1c).…”

Section: ■ Experimental Sectionmentioning

confidence: 99%

Fabrication of Fully Positively Charged Layer-by-Layer Polyelectrolyte Nanofilms with pH-Dependent Swelling Properties

Zhang,

Zeng,

Matsusaki

2024

Langmuir

View full text Add to dashboard Cite

Nanofilms fabricated by layer-by-layer (LbL) assembly from polyelectrolytes (PEs) are important materials for various applications. However, PE films cannot retain the charges along the polymer chains during fabrication, resulting in a low charge density. In this study, the preparation of LbL nanofilms with preserved positive charges via a controllable and efficient approach was achieved. To fabricate fully positively charged (FPC) LbL nanofilms, a polycation, poly-L-lysine, was partially grafted with azide and alkyne groups. Through coppercatalyzed azide−alkyne cycloaddition and the LbL procedure, nanofilms were fabricated with all of the individual layers covalently bonded, improving the pH stability of the nanofilms. Because the resulting nanofilms had a high charge density with positive charges both inside and on the surface, they showed unique pH-dependent swelling properties and adsorption of negatively charged molecules compared with those of traditional polyelectrolyte LbL nanofilms. This kind of FPC nanofilm has great potential for use in sensors, diagnostics, and filter nanomaterials in the biomedical and environmental fields.

show abstract

Commodity Sales Data Analysis Based on Qoo10 Platform

Yang

Pan

Xiang

2020

Data Processing Techniques and Applications for Cyber-Physical Systems (DPTA 2019)

View full text Add to dashboard Cite

Rate of a Click Chemistry reaction under catalysis by trace‐amounts of copper as evaluated by NMR spectroscopy

Cited by 3 publications

References 8 publications

Fabrication of Fully Negatively Charged Layer-by-Layer Nanofilms with pH-Induced Remarkable Swelling–Shrinking Properties

Fabrication of Fully Negatively Charged Layer-by-Layer Nanofilms with pH-Induced Remarkable Swelling–Shrinking Properties

Fabrication of Fully Positively Charged Layer-by-Layer Polyelectrolyte Nanofilms with pH-Dependent Swelling Properties

Commodity Sales Data Analysis Based on Qoo10 Platform

Contact Info

Product

Resources

About