Rate of isolation of streptococcus species from children with bacterial infections: an indication for introduction of streptococcal vaccines

Abstract

Version 3.5.1. Statistical significance was set at p < 0.05.A total of 2,247 samples were received during the study period. Of the 1,242 bacteria isolated, 502 (40.4%) were , 232 (18.7%) were and 146 (11.8%) were Streptococcus species: 78 were isolated from blood, 9 from sputum, 11 from throat swabs and 28 from other sites while urine and eye swabs had 10 each. One hundred and six (72.6%) of the streptococci were from children aged 5 years and below. Most of the Streptococci (88.1%) were untyped. Among the 17 Streptococcal isolates typed, 10 were a n d t h r e e w e r e g r o u p B Streptococcus.S t r e p t o c o c c a l infections remain an important cause of severe disease in children in Nigeria. The use of effective, safe and affordable vaccine could significantly reduce morbidity from these infections, thus suggesting the need for more studies to conclude o n s t r e Abstract Background: Streptococcus pneumoniaeObjective: M a t e r i a l s a n d M e t h o d s :

Throat Carrier Rate of Streptococcus pneumoniae among Students Living in Hostels in a Higher Institution

“…Some members of the normal flora produce antibacterial chemicals (bacteriocins) as a side product of their metabolism, thus generating a local antibiotic effect which hinders the invader (The Crohnie, htt://primer.crohn.ie/ human-normal-flora). Streptococcal infection has been identified as an important cause of severe disease in Nigeria (Onalo et al, 2011). Ceftriaxone 30 22 0 0 100 Ceftazidime 30 22 0 0 100 Cefuroxime 30 22 0 0 100 Erythromycin 30 22 0 0 100 Cotrimoxazole 25 18 4 18 82 Ampicillin 30 22 0 0 100 Tetracycline 30 15 7 32 68 Record are however scanty on characterization of streptococcal species in bacterial infections in Nigeria (Onalo et al, 2011).…”

“…Streptococcal infection has been identified as an important cause of severe disease in Nigeria (Onalo et al, 2011). Ceftriaxone 30 22 0 0 100 Ceftazidime 30 22 0 0 100 Cefuroxime 30 22 0 0 100 Erythromycin 30 22 0 0 100 Cotrimoxazole 25 18 4 18 82 Ampicillin 30 22 0 0 100 Tetracycline 30 15 7 32 68 Record are however scanty on characterization of streptococcal species in bacterial infections in Nigeria (Onalo et al, 2011). In a study of Streptococcal species identification of bacterial infection in Abuja (Nigeria), the researchers reported that 58.8% (10 out of 17 isolates of Streptococcus typed) of streptococcal infection were caused by Streptococcus pneumoniae (Onalo et al, 2011).…”

“…Streptococcus pneumoniae was responsible for 8.8% cases of otitis media among children in Ile-Ife (Ako-Nai, 2002), 4.6 % conjunctivitis among children in Ibadan (Adeyeba et al, 2010), 7.5% cases of bacterial infections in children in Abuja (Onalo et al, 2011). In South Africa, 74.5% (35 children out of 47) children with otitis media were due to Streptococcus pneumoniae (Huebner et al, 2003).…”