Rate of severe ovarian damage following surgery for endometriomas

Benaglia, Laura; Somigliana, Edgardo; Vighi, Valentina; Vegetti, Walter; Vercellini, Paolo; Ragni, G

doi:10.1016/j.fertnstert.2009.07.232

Cited by 19 publications

(22 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…50 and it is well known that women with endometriotic cysts have an increased risk of ovarian insufficiency, particularly if bilateral cysts have been removed. 37,[51][52][53] Several mechanisms have been described to explain the quantitative alteration of ovarian reserve after cystectomy for endometrioma; accidental removal of healthy ovarian tissue during cystectomy, vascular compromise due to electrocoagulation, local inflammation and autoimmune reaction, expertise of the surgeon, extent of the disease and number of surgical interventions may have impact on ovarian reserve. Even at the hand of skilled surgeon there is a progressive decline of AMH after endometriotic cystectomy.…”

Section: Discussionmentioning

confidence: 99%

Endometrioma is a Responsible Factor for Reduced Ovarian Reserve

Begum

Ehsan²,

Ehsan³

et al. 2016

Bangladesh J Obstet Gynaecol

View full text Add to dashboard Cite

Objective (s): The aim of the study was to assess ovarian reserve (OR) of patients with endometrioma and to explore the differences of ovarian reserve in age matched group of infertile patients without endometrioma.Materials and methods: This prospective analytic study was done in Infertility Care and Research Center, between January 2013 and December 2015 to assess the ovarian reserve of patients with endometrioma. During this period 105 patients of endometriosis with endometrioma were selected for study. Selection criteria were: no history of previous surgery, <36 years of age, no history of endocrine problems, no history of recent medical treatment for this condition within 6 months and no history of irregular menstruation. For ovarian reserve testing we assessed serum FSH, E2 and AMH. Patient of same age group who had no emdometrioma, no history of any surgery, no menstrual irregularity, endocrine disorder or any other medical diseases were taken as control to compare the ovarian reserve between these two groups. For control group also we did the same tests. Data was analyzed by SPSS package. One-way ANOVA test was done for test of significance. A p-value of <0.05 was considered as significant.Results: There was no difference in characteristics of patients of both groups regarding age, type of infertility and duration of infertility. Size of the endometriotic cysts were variable and average diameter of cyst was 6.2 ±2.32 cm. Most (58.10%) of the cysts were unilateral. There is a significant difference of FSH and AMH level between the groups. FSH of endometrioma and non-endometrioma group was 7.9 ±1.17 and 7.1 ±1.05 mIU/mL respectively with a p value of 0.029. Similar difference was present in AMH level, which was 2.42 ±.63 and 2.98 ±.88 ng/ mL in endometrioma and non-endometrioma group respectively with a p value of 0.020.Conclusion: This small study shows a reduced ovarian reserve in patients with endometrioma in comparison to patients of same parameters without endometrioma. It suggests that there is an association of presence of ovarian endometrioma and reduced ovarian reserveBangladesh J Obstet Gynaecol, 2015; Vol. 30(2) : 98-104

show abstract

Section: Discussionmentioning

confidence: 99%

Endometrioma is a Responsible Factor for Reduced Ovarian Reserve

Begum

Ehsan²,

Ehsan³

et al. 2016

Bangladesh J Obstet Gynaecol

View full text Add to dashboard Cite

show abstract

“…Many studies showed that after excision there was an increased risk of diminished ovarian reserve [47,48] .…”

Section: Cystectomymentioning

confidence: 99%

Ovarian Endometrioma and Infertility

2017

ARC Journal of Gynecology and Obstetrics

View full text Add to dashboard Cite

“…the pool of little antral follicles inside both ovaries, which are already compromized by the development of at least one or more endometriomas within the gonad (17,18).…”

Section: Histopathological Evaluationmentioning

confidence: 99%